Effect of aspirin combined with atorvastatin on prevention of the recurrence of cerebral infarction
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摘要: 目的 研究抗血小板药物阿司匹林与阿托伐他汀联合用药对预防脑梗死复发的临床效果.方法 将116例脑梗死患者随机分成2组,均给予脑梗死首发常规治疗,治疗组同时口服阿托伐他汀钙20 mg/d及阿司匹林肠溶片100 mg/d,对照组仅晚间口服阿司匹林肠溶片100 mg/d.比较治疗12个月后2组患者的脑梗死复发率及治疗前后颈动脉斑块变化情况.结果 治疗12个月后,治疗组复发率(5.2％)显著低于对照组(19.0％),治疗组不稳定斑块率(24.1％)亦显著低于对照组(41.4％).结论 阿司匹林与阿托伐他汀联合用药后可降低脑梗死患者复发率及不稳定斑块率,其在预防脑梗死复发事件上具有明显的作用.
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