Application of image-guided radiotherapy in treating patients with cervical cancer
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摘要: 目的 探讨中晚期宫颈癌患者应用图像引导放射治疗(IGRT)技术,在提高靶区剂量与减少正常组织受量方面的价值.方法 30例中晚期宫颈癌患者,均给予全程IGRT放疗同步化疗.治疗结束后3个月评价近期疗效,随访评价毒副反应发生情况.观察直肠、小肠和膀胱的受照射剂量和体积.结果 30例患者均完成全程的IGRT,近期疗效显示:CR 26例,PR 4例.1至2年生存率为100％.放疗靶区较精确,OAR的受照剂量为:小肠31.68 Gy;直肠37.19 Gy;膀胱30.13 Gy.毒副反应主要为急、慢性消化道反应和急、慢性血液系统反应.结论 在宫颈癌治疗中,IGRT放疗技术可以提高肿瘤放疗的精准性,达到最大程度杀灭肿瘤和保护正常组织器官功能,毒副反应可耐受.
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Mackie T R, Kapatoes J, Ruchala K. Image guidance for precise conformal radi otherapy [J]. International Journal of Radiation Oncology, Biology, Physics, 2003(1):89. Georg P, Georg D, HillbrandM. Factors influencing bowel sparing in intensity modulated whole pelvic radiotherapy for gynaecologicaI malignancies [J]. Radiotherapy and Oncology, 2006(1):19. Paley P J, Goff B A, Minudri R. The prognostic significance of radiation dose and residual tumor in the treatment of barrel shaped endo-phytic cervical carcinoma [J]. Gynecologic Oncology, 2000(3):373. Merck D, Tracton G, Saboo R. Training models of anatomic shape variability [J]. Medical Physics, 2008(8):3584. Eifel P J, levenback C, Wharton J F. Tine course and incidence of late complications in patients treated with radiationtherpy for FIGO stage IB carcinoma of the uterine cervix [J]. International Journal of Radiation Oncology, Biology, Physics, 1995(5):1289. Com B W, Lanciano R M, Greven K M. Impact of improved irradiation technique age and lymph node sampling on the severe complication rate of surgically staged endometrial cancer patients amultivarirate analysis [J]. Journal of Clinical Oncology, 1994(3):510.
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