胞外信号调节激酶与血管内皮生长因子在非小细胞肺癌组织中表达的相关性研究

丁乾, 陈静, 李跃华, 朱芳, 黄晶, 曹如波, 彭纲

丁乾, 陈静, 李跃华, 朱芳, 黄晶, 曹如波, 彭纲. 胞外信号调节激酶与血管内皮生长因子在非小细胞肺癌组织中表达的相关性研究[J]. 实用临床医药杂志, 2012, (19): 16-18,22.
引用本文: 丁乾, 陈静, 李跃华, 朱芳, 黄晶, 曹如波, 彭纲. 胞外信号调节激酶与血管内皮生长因子在非小细胞肺癌组织中表达的相关性研究[J]. 实用临床医药杂志, 2012, (19): 16-18,22.
DING Qian, CHEN Jing, LI Yuehua, ZHU Fang, HUANG Jing, CAO Rubo, PENG Gang. The correlation of expression of ERK5 with VEGF in non small cell lung cancer[J]. Journal of Clinical Medicine in Practice, 2012, (19): 16-18,22.
Citation: DING Qian, CHEN Jing, LI Yuehua, ZHU Fang, HUANG Jing, CAO Rubo, PENG Gang. The correlation of expression of ERK5 with VEGF in non small cell lung cancer[J]. Journal of Clinical Medicine in Practice, 2012, (19): 16-18,22.

胞外信号调节激酶与血管内皮生长因子在非小细胞肺癌组织中表达的相关性研究

基金项目: 中央高校基本科研业务费专项资金资助,中国高校医学期刊临床专项资金
详细信息
  • 中图分类号: R734.2

The correlation of expression of ERK5 with VEGF in non small cell lung cancer

  • 摘要: 目的 探讨胞外信号调节激酶(ERK5)以及血管内皮生长因子(VEGF)在非小细胞肺癌(NSCLC)组织中的表达情况及2者之间的相关性.方法 应用免疫组织化学SABC法检测88例NSCLC组织及16例良性肺疾病组织中ERK5和VEGF的表达情况,并与临床病理特征进行统计学分析.结果 ERK5及VEGF在NSCLC中的表达均高于良性肺疾病,与患者的年龄、性别和组织类型均没有相关性,而与肿瘤TNM分期、分化程度、淋巴结转移密切相关.ERK5与VEGF两者之间表达呈正相关.结论 ERK5和VEGF可能协同参与NSCLC的发生、发展.
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  • 发布日期:  2013-01-15

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