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摘要: 病毒性脑炎是儿科临床常见的中枢性感染性疾病,其发病过程涉及多种细胞因子.作者对15例急性中枢神经系统感染的患儿进行脑脊液IL-6、TNF-α、INF-γ含量进行测定,并探讨其临床意义,现将报道如下.
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吴瑞萍, 胡亚美, 江载芳. 诸福棠实用儿科学 [M]. 北京:人民卫生出版社, 2002.759. Bociaga-Jasik M, Ciesla A, Kalinowska-Nowak A. Role of IL-6 and neopterin in the pathogenesis of herpetic encephalitis [J]. Pharmcol Rep, 2011(5):1203. Vichaya E G, Young E E, Frazier M A. Social disruption induced priming of CNS inflammatory response to Theiler's virus is dependent upon stress induced IL-6 release [J]. Journal of Neuroimmunology, 2011, (1-2):44. Libbey J E, Kennett N J, Wilcox K S. Interleukin-6, produced by resident cells of the central nervous system and infiltrating cells, contributes to the development of seizures following viral infection [J]. Journal of Virology, 2011, (14):6913. Kansagra S M, Gallentine W B. Cytokine storm of acute necrotizing encephalopathy [J]. Pediatric Neurology, 2011(6):400. Lazear H M, Pinto A K, Vogt M R. Beta interferon controls West Nile virus infection and pathogenesis in mice [J]. Journal of Virology, 2011, (14):7186. Alammar L, Gama L, Clements J E. Simian immunodeficiency virus infection in the brain and lung leads to differential type Ⅰ IFN signaling during acute infection [J]. Journal of Immunology, 2011(7):4008. Poponnikova T V, Bedareva TIu, Vakhrameeva T N. The cytokine profile in the acute period of tick-borne neuroinfections in children [J]. Nevropatologii i Psikhiatrii Imeni S S Korsakova, 2010, (5Pt 1):9.
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