冠状动脉旁路移植术同期干细胞移植治疗冠心病慢性心衰的中期结果

冠状动脉旁路移植术同期干细胞移植治疗冠心病慢性心衰的中期结果[J]. 实用临床医药杂志, 2009, (9): 1-4,18.
引用本文: 冠状动脉旁路移植术同期干细胞移植治疗冠心病慢性心衰的中期结果[J]. 实用临床医药杂志, 2009, (9): 1-4,18.
Midterm results of coronary artery bypass graft combined with autologous stem cell transplant treatment in chronic heart failure caused by coronary artery disease[J]. Journal of Clinical Medicine in Practice, 2009, (9): 1-4,18.
Citation: Midterm results of coronary artery bypass graft combined with autologous stem cell transplant treatment in chronic heart failure caused by coronary artery disease[J]. Journal of Clinical Medicine in Practice, 2009, (9): 1-4,18.

冠状动脉旁路移植术同期干细胞移植治疗冠心病慢性心衰的中期结果

基金项目: 国家支撑计划资助项目,北京市科技计划项目
详细信息
  • 中图分类号: R.541.4

Midterm results of coronary artery bypass graft combined with autologous stem cell transplant treatment in chronic heart failure caused by coronary artery disease

  • 摘要: 目的 利用冠状动脉旁路移植手术同期经冠状动脉桥血管内移植自体骨髓单个核细胞的方法 治疗冠心病陈旧性心肌梗死伴慢性心功能不全患者,评价治疗的安全性和中期临床效果.方法 选择需要外科手术治疗的冠心病陈旧心梗伴左室功能不全患者,应用冠状动脉旁路移植手术同期经冠状动脉桥血管内移植自体骨髓单个核细胞的治疗方法.评价干细胞移植后左室功能改变、不良事件、生存时间和中期随访情况.结果 全组19例患者接受冠状动脉旁路移植术同期经冠状动脉桥血管内移植干细胞治疗.1例术后第3天因脑栓塞死亡.全组患者治疗后早期无心梗发生,无肝、肾功能衰竭,无新发恶性心律失常出现.18例患者平均随访2年全部存活,超声检测左室射血分数上升,心功能和心绞痛症状明显改善并具有统计学意义.结论 冠状动脉旁路移植术同期经冠状动脉桥血管内移植自体骨髓单个核细胞治疗冠心病陈旧性心肌梗死的方法是可行的.手术后早、中期随访结果观察,此种治疗是安全的.
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出版历程
  • 发布日期:  2009-11-29

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