心肌缺血预适应对心肌梗死的临床影响

CLINICAL EFFECTS OF MYOCARDIAL ISCHEMIC-PRECONDITION ON MYOCARDIAL INFARCTION

摘要: 目的 :研究心肌缺血预适应对心肌梗死的临床影响。方法 :选取 13 0例资料完整的急性心肌梗死病例 ,按梗死前有无心肌缺血、心绞痛分为A、B组 ,进行分析、比较。结果 :A组心肌梗死范围、心肌酶峰值、严重心律失常、左心衰竭、休克的发生率及病死率均明显低于B组。结论 :心肌缺血预适应对心肌梗死的临床作用表现在限制梗死面积扩大 ,保护梗死后心脏功能 ,减少严重心律失常的发生

Abstract: Objective:To study the clinical effects of myocardial ischemic-precondition on myocardial infarction. Methods:One hundred and thirty patients were divided into two groups.Group A with myocardial ischemia or angina pectoris before myocardial infarction and group B without it.And then compare and analysis the results. Results:The myocardial infarction size,mortality rate and incidence of serious complications(such as left heart failure,cardiac arrhythmias and shock)of group A are sigificiantly lower than group B. Our data indicated that myocardial ischemic-precondition may restrict the amplification of myocardial infarction size,protect the post-infarctional cardiac function,and decrease the incidence of serious cardiac arrhythmias.