司帕沙星与洛美沙星片剂临床疗效及安全性的比较

A COMPARISON ON CLINICAL EFFICACY AND SAFETY OF SPARFLOXACIN AND LOMEFLOXACIN

摘要: 目的：评价抗菌新药司帕沙星片剂的临床疗效及安全性。方法：以洛美沙星片剂为对照，在73例急性细菌性感染患者中进行随机对照性研究。结果：试验组的痊愈率（84.21%）、有效率（92.11%）均高于对照组的痊愈率（65.71%）和有效率（82.86%），但统计学差异无显著性（P＞0.05）。试验组患者不良反应发生率（5．3%）显著低于对照组（14.3%），P＜0.05。结论：在细菌感染性疾病的治疗中，司帕沙星片剂优于洛美沙星片剂。

Abstract: Aim: to evaluate the clinical efficacy and safety of Sparfloxacin tablets, a random con-trast study compared with Lomefloxacin tablts in 73 patients with acute infections caused by bacteria wasperformed. Result: the recovered rate (84. 21 % ) and effective rate (92. 11 % ) in the test group werehigher than the recovered rate (65. 71 % ) and effective rate (82. 86% ) in the contrast group, thoughthere were no significant differance statistically (P O. O5). The side - effetive rate was 5. 3% in thetest group, which was lower than that (14. 3% ) in control group (P 0. 05 ). Conclusion:Sparfloxacin tablets are better than Lomefloxacin tablets in treating acute infectious-diseases caused by bac-teria.