不稳定型心绞痛可溶性白介素-2受体变化的临床意义

CLINICAL SIGNIFICANCE OF THE CHANGE OF SOLUBLE INFERLEUKIN-2 RECEPTOR IN UNSTABLE ANGINA

摘要: 采用ELISA法测定19例不稳定型心绞痛和21例稳定型心绞痛患者血清可溶性白介素2一受体（511--2R），并与16名健康者相对照。结果发现不稳定型心绞痛患者sIL-2R水平显著高于稳定型心绞痛患者和健康者，病情控制后sIL-2R水平显著下降。提示免疫炎症反应在不稳定型心绞痛的发生过程中有重要作用，检测血清sIL-2R有助于不稳定型心绞痛的早期诊断。

Abstract: Soluble interleukin - 2 receptor (sIL - 2R) in 19 patients with proven unstable anginawas measured in plasma by ELISA- The result was compared with those of 21 with stable allgina and 16healthy subjects. The level of sIL - 2R in patients with unstable angina was higher than in patients withstable angina and control subjects, and it decreased significantly after angina was controled. This resultsuggests that immune system - mediated inflammatory might play an important role in the pathoplysiol0gyof unstable angina- The detection to serum sIL - 2R could help for diagnosis of unstable angina.