Investigation on serum 25-hydroxy-vitamin D levels in 4 013 pregnant women in middle or late stages
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摘要: 目的 调查并分析4 013名孕妇妊娠中晚期的血清25-羟维生素D［25-(OH)D］水平。 方法 选取产检的4 013名孕妇作为研究对象,均接受妊娠中晚期血清25-(OH)D水平检测,观察本组孕妇妊娠中期、晚期血清25-(OH)D水平和缺乏率,并分析妊娠晚期服用维生素D情况与血清25-(OH)D缺乏的相关性。 结果 本组孕妇的妊娠中期血清25-(OH)D平均水平为(42.08±15.26)nmol/L, 缺乏率为65.79%, 妊娠晚期血清25-(OH)D平均水平为(40.50±15.91)nmol/L, 缺乏率为73.44%; 妊娠晚期坚持每天服用≥400 IU剂量维生素D者1 406名(35.04%), 偶尔服用者1 057名(26.34%), 未服用者1 550名(38.62%)。 结论 半数以上孕妇在妊娠中晚期会发生维生素D缺乏,日常营养干预和适当补充维生素D能较好地改善其维生素D缺乏现状,从而降低妊娠期相关并发症的发生率。
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关键词:
- 维生素D /
- 血清25-羟维生素D /
- 孕妇 /
- 妊娠期
Abstract: Objective To investigate and analyze the levels of serum 25-hydroxy-vitamin D［25-(OH)D］ in 4 013 pregnant women in middle or late stages. Methods A total of 4 013 pregnant women were selected as research objects and all performed detection of serum 25-(OH)D. The serum 25-(OH)D levels and deficiency rates of pregnant women in the second and third trimester of pregnancy were observed, and the correlation between vitamin D intake in the third trimester and serum 25-(OH)D deficiency was analyzed. Results The average levels of serum 25-(OH)D in the second trimester and third trimester were(42.08±15.26)nmol/L and(40.5±15.9)nmol/L, respectively, and their deficiency rates were 65.79% and 73.44%, respectively. There were 1 406(35.04%)pregnant women in third trimester of pregnancy taking vitamin D at a dosage of 400 IU or above daily, 1 057(26.34%)occasionally taking vitamin D, and 1 550(38.62%)taking no vitamin D. Conclusion Vitamin D deficiency probably occurs in more than a half pregnant women in the middle and late pregnancy. The daily nutritional intervention and appropriate vitamin supplementation can improve status of the vitamin D deficiency, and reduce the incidence of related complications during pregnancy.-
Keywords:
- vitamin D /
- serum 25-hydroxy-vitamin D /
- pregnant women /
- duration of pregnancy
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