Clinical efficacy of herbal fumigation on hand-foot syndrome after chemotherapy in colorectal cancer patients
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摘要: 目的 观察中药熏洗治疗卡培他滨化疗后手足综合征的疗效。 方法 选取因口服卡培他滨出现Ⅱ级手足综合征的结直肠癌患者84例,随机分为治疗组和对照组,每组42例。对照组给予口服维生素B6及甲钴胺治疗; 治疗组在口服药物治疗的基础上加用中药熏洗治疗,比较2组治疗后疗效情况。 结果 对照组总有效率64.3%, 其中治愈率38.1%; 治疗组总有效率90.5%, 其中治愈率66.7%, 2组总有效率、治愈率差异具有统计学意义(P<0.05)。 结论 针对卡培他滨化疗后手足综合征患者在口服药物治疗基础上加用中药熏洗可提高治疗有效率和治愈率。Abstract: Objective To observe the effect of herbal fumigation on hand-foot syndrome after capecitabine chemotherapy. Methods Eighty-four colorectal cancer patients with Ⅱ degree of hand-foot syndrome induced by oral capecitabine for chemotherapy were randomly divided into control group and treatment group. Patients in the control group orally administrated vitamin B6 and mecobalamine, and those in the treatment group was additionally given herbal fumigation based on oral administration of drugs. The curative effects of the two groups were compared after treatment. Results The total effective rate was 64.3% in the control group, and 90.5% in the treatment group; the cure rate was 38.1% in the control group, and 66.7% in the treatment group, there were statistically significant differences in total effective rate and cure rate between the two groups(P<0.05). Conclusion Fumigation with traditional Chinese medicine based on oral administration of drugs can improve the effective rate and cure rate of hand-foot syndrome.
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Keywords:
- capecitabine /
- hand-foot syndrome /
- herbal fumigation /
- vitamin B6 /
- mecobalamine /
- colorectal cancer
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