Effect observation of Xingqi Huoxue Lidan Decoction combined with laparoscopic cholecystectomy in the treatment of patients with cholecystitis
-
摘要: 目的 观察中医行气活血利胆汤联合腹腔镜胆囊切除术治疗胆囊炎的临床效果。 方法 选取胆囊炎患者90例,随机分为手术组和联合组,每组45例。2组患者均行腹腔镜胆囊切除术,联合组术后第2天服用行气活血利胆汤治疗。比较2组患者的手术时间、手术出血量、首次肛门排气时间、住院时间。比较2组患者手术前、手术后72 h血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-10(IL-10)水平。比较2组并发症发生率。 结果 2组患者的手术时间、手术出血量、首次肛门排气时间、住院时间比较,差异均无统计学意义(P>0.05)。术后72 h, 联合组患者血清CRP、TNF-α、IL-6、IL-10水平低于手术组患者,差异均有统计学意义(P<0.05)。联合组的并发症发生率为4.44%, 低于手术组的11.11%, 但差异无统计学意义(P>0.05)。 结论 行气活血利胆汤联合腹腔镜胆囊切除术治疗胆囊炎安全、有效,可减轻手术引起的炎症反应,促进患者术后康复。Abstract: Objective To observe the clinical effect of Xingqi Huoxue Lidan Decoction combined with laparoscopic cholecystectomy in the treatment of patients with cholecystitis. Methods Ninety patients with cholecystitis were selected and randomly divided into surgery group and combined group, with 45 cases in each group. Both groups were treated with laparoscopic cholecystectomy, and the combined group was treated with Xingqi Huoxue Lidan Decoction on the second day after operation. Operation time, the amount of bleeding, the time of the first anal exhaust and the length of hospital stay were compared between two groups. The levels of serum C-reactive protein(CRP), tumor necrosis factor-α(TNF-α), interleukin-6(IL-6), interleukin-10(IL-10)were compared between two groups before operation and 72 hours after operation. Incidence of complications was compared between two groups. Results There were no significant differences in operation time, the amount of bleeding, the time of the first anal exhaust and the length of hospital stay between the two groups(P>0.05). At 72 hours after operation, the levels of CRP, TNF-α, IL-6 and IL-10 in the combined group were significantly lower than those in the surgery group(P<0.05). The incidence of complications in the combined group was 4.44%, which was lower than 11.11% in the operation group, but there was no significant difference(P>0.05). Conclusion Xingqi Huoxue Lidan Decoction combined with laparoscopic cholecystectomy is effective and safe in the treatment of patients with cholecystitis, which can reduce the inflammatory reaction caused by operation and promote the postoperative recovery of patients.
-
-
尚培中, 苗建军, 李晓武. 急性和亚急性胆囊炎腹腔镜手术治疗的安全策略[J]. 中华普通外科学文献: 电子版, 2019, 13(6): 426-429. 伍万权. 腹腔镜胆囊切除术胆道损伤相关因素分析及预防[J]. 中华肝脏外科手术学电子杂志, 2019, 8(6): 538-541. 王琮. 调气活血疏利三焦法治疗鼓胀病1例[J]. 中西医结合肝病杂志, 2019, 29(3): 265-266. 中国中西医结合学会消化系统疾病专业委员会. 胆石症中西医结合诊疗共识[J]. 中国中西医结合杂志, 2011, 31(8): 1041-1043. GURGENIDZE M R, KILADZE M A, BERIASHVILI Z A, et al. Miniinvasive surgical interventions in management of cholelithiasis A retrospective study[J]. Ann Ital Chir, 2017, 88: 170-177.
ITOI T, TSUCHIYA T, SOFUNI A, et al. Development of EUS-guided gallbladder drainage and current indications[J]. Endosc Ultrasound, 2018, 7(2): 76-78.
ESENDAĜLI G, AKARCA F G, BALCI S, et al. A retrospective evaluation of the epithelial changes/lesions and neoplasms of the gallbladder in Turkey and a review of the existing sampling methods: a multicentre study[J]. Turk Patoloji Derg, 2018, 34(1): 41-48.
JUSTO I, MARCACUZCO A, NUTU O A, et al. A retrospective analysis of patients with gallbladder cancer: surgical treatment and survival according to tumor stage[J]. Rev Esp Enferm Dig, 2018, 110: 485-492.
王文林, 彭海燕. 清热活血法治疗胆囊癌术后瘀热证[J]. 中国中医药信息杂志, 2018, 25(11): 99-102. 陈晨, 任明, 徐鲲, 等. 行气活血方对腹腔镜胆囊切除术后患者凝血功能及恢复情况的影响[J]. 贵州医药, 2018, 42(10): 1190-1191. 牛璐璐, 闫彦峰, 柴辉, 等. 刘国安治疗胆囊切除术后综合征经验[J]. 中国中医药信息杂志, 2018, 25(12): 114-116. 高扬, 耿鹏, 郭书娟, 等. 加味大承气汤辅助腹腔镜胆囊切除术治疗结石性胆囊炎疗效及对患者消化功能的影响[J]. 陕西中医, 2019, 40(4): 493-495. 单秋旺, 霍鹏, 李琳琳, 等. 中药消炎利胆汤联合常规西药对胆结石微创术后患者胆囊功能、炎性因子和临床疗效的影响[J]. 湖南中医药大学学报, 2019, 39(11): 1399-1402. CASTRO C M, SANTIBAÑEZ S P, RIVAS T C, et al. Totally laparoscopic radical resection of gallbladder cancer: technical aspects and long-term results[J]. World J Surg, 2018, 42(8): 2592-2598.
UCHINO Y, TAKETANI S, HIRAYU N, et al. A case report of neuroendocrine carcinoma in the gall bladder showing recurrence shortly after surgery[J]. Gan To Kagaku Ryoho, 2018, 45(4): 631-633.
HAGHIGHATAFSHAR M, AMIRKHANI Z, GHAEDIAN T. Role of hepatobiliary scintigraphy in the diagnosis of gallbladder agenesis; A case report and brief review of literature[J]. Middle East J Dig Dis, 2018, 10(2): 109-113.
PERISETTI A, RAGHAVAPURAM S, THARIAN B, et al. Pure squamous cell carcinoma of the gallbladder masquerading as a hepatic mass[J]. Cureus, 2018, 10(1): e2011-e2018.
SARIKAYA I, ELGAZZAR A H, ALFEELI M A, et al. Gallbladder activity on sodium fluoride positron emission tomography/computed tomography bone scan[J]. World J Nucl Med, 2018, 17(3): 201-203.
杨正弦, 何智彬. 中西医结合治疗胆结石患者中IL-4、IL-10及CD3+、CD4+、CD8+水平的变化观察——芪术利胆消石汤联合腹腔镜胆囊切除术[J]. 中国中西医结合外科杂志, 2019, 25(6): 895-898. 毛艳平, 张能平. 利胆排石汤辅助胆道镜取石术治疗慢性胆囊炎合并胆结石疗效及对胆汁成石成分、炎性细胞因子的影响[J]. 现代中西医结合杂志, 2019, 28(4): 406-408.
计量
- 文章访问数: 339
- HTML全文浏览量: 97
- PDF下载量: 12
下载:
苏公网安备 32100302010246号
