Value of high-frequency ultrasound in the diagnosis of papillary thyroid carcinoma in children
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摘要: 目的 分析高频彩色多普勒超声在儿童甲状腺乳头状癌诊断中的应用价值。 方法 回顾性分析150例经手术病理证实为甲状腺乳头状癌患儿的临床资料。术前均给予高频彩色多普勒超声、常规二维超声检查,统计超声诊断符合率,并分析患儿高频彩色多普勒超声声像图特征。 结果 高频彩色多普勒超声检查符合率为70.00%, 显著高于常规二维超声的54.00%(P<0.05)。以结节单发为主、后方回声衰减、形态不规则、边界不清晰、无声晕、内部低回声、回声不均匀、无囊性改变,多见微小钙化与同一项目其他声像图特征比较,差异有统计学意义(P<0.05)。150例甲状腺乳头状癌患儿超声声像图显示,血流分布为3级的患儿占比高于1级、2级,差异有统计学意义(P<0.05)。150例甲状腺乳头状癌患儿中,伴颈部淋巴结肿大28例(18.67%), 呈低回声、无淋巴门、伴微小钙化差异有统计学意义(P<0.05)。 结论 高频彩色多普勒超声对儿童甲状腺乳头状癌具有一定的诊断价值。结合二维超声能够明确肿瘤特点,为手术治疗提供可靠依据。Abstract: Objective To analyze the value of high-frequency ultrasound in the diagnosis of papillary thyroid carcinoma in children. Methods The clinical data of 150 children with papillary thyroid carcinoma confirmed by surgical pathological diagnosis was retrospectively analyzed. High-frequency color Doppler ultrasound and conventional two-dimensional ultrasound were separately given to these patients before surgery. Their coincidence rates of ultrasound were calculated and analyzed. Ultrasonographic features of children diagnosed by high-frequency color Doppler ultrasound were analyzed. Results The coincidence rate of high-frequency ultrasound examination was 70.00%, which was significantly higher than 54.00% of conventional two-dimensional ultrasoundexamination(P<0.05). The ultrasonographic findings were characterized by single nodule as main occurrence, rear echo attenuation, irregular morphology, unclear boundary, no sound halo, internal low echo, uneven echo, no cystic change, and more common occurrence of microcalcification, which showed significant differences when compared to the other items of ultrasonographic findings(P<0.05). Ultrasonographic findings of 150 papillary thyroid carcinoma showed that the proportion of children with blood flow distribution as grade 3 significantly exceeded those with grade 1 and grade 2(P<0.05). Out of 150 children with papillary thyroid carcinoma, there were 28 cases(18.67%)complicating with lymphadenectasis, and a low echo, no lymphatics, and slight calcification showed significant differences(P<0.05). Conclusion High-frequency color Doppler ultrasound is of certain value in diagnosis of children with papillary thyroid carcinoma. Combined with two-dimensional ultrasound, it can clarify the characteristics of the tumors and provide a basis for surgical treatment.
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