Analgesic effect of sufentanil combined with ropivacaine in treatment of puerperas with cesarean section
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摘要: 目的 观察舒芬太尼联合罗哌卡因对剖宫产产妇的镇痛效果。 方法 将100例剖宫产产妇随机分为观察组和对照组,每组50例。观察组采用舒芬太尼联合罗哌卡因镇痛,对照组采用罗哌卡因镇痛。比较2组术后2、6、12、24 h时的视觉模拟疼痛量表(VAS)评分、生活质量评分表(QOL)评分。记录2组患者按压镇痛泵次数和所用药物剂量、下肢运动神经阻滞时间、满意度情况。比较2组不良反应发生率。 结果 观察组患者术后2、6、12、24 h时VAS评分均低于对照组,差异有统计学意义(P<0.05)。观察组患者术后2、6、12、24 h时QOL评分均高于对照组,差异有统计学意义(P<0.05)。观察组按压镇痛泵次数和所用药物剂量、下肢运动神经阻滞时间均少于对照组,满意度评分高于对照组,差异有统计学意义(P<0.05)。观察组术后不良反应发生率为6.00%, 低于对照组的20.00%, 差异有统计学意义(P<0.05)。 结论 舒芬太尼联合罗哌卡因镇痛效果显著,可提高剖宫产术产妇的生活质量,且不良反应较少。Abstract: Objective To observe the analgesic effect of sufentanil combined with ropivacaine in treatment of puerperas with cesarean section. Methods Totally 100 puerperas with cesarean section were randomly divided into observation group and control group, with 50 cases in each group. The observation group was given sufentanil combined with ropivacaine for analgesia, while the control group was given ropivacaine for analgesia. The scores of Visual Analogue Scale(VAS)and Quality of Life(QOL)score were compared between the two groups at 2, 6, 12 and 24 h after operation. The times of pressing analgesia pump and drug dosage, duration of block for motor nerve of lower limbs and satisfaction degree were recorded in both groups. The incidence of adverse reactions was compared between the two groups. Results The VAS scores of the observation group were significantly lower than those of the control group at 2, 6, 12, 24 h after operation(P<0.05). The QOL scores of the observation group were significantly higher than those of the control group at 2, 6, 12 and 24 h after operation(P<0.05). The times of pressing analgesia pump, drug dosage and duration of block for motor nerve of lower limbs in the observation group were significantly less than those in the control group, and the score of satisfaction degree was significantly higher than that in the control group(P<0.05). The incidence of adverse reactions in the observation group was 6.00%, which was significantly lower than 20.00% in the control group(P<0.05). Conclusion Sufentanil combined with ropivacaine has a significant analgesic effect in treatment of puerperas with cesarean section, which can improve the quality of life and cause less adverse reactions.
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Keywords:
- sufentanil /
- ropivacaine /
- cesarean section /
- pain /
- quality of life /
- nerve block
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匡丕雄. 不同剂量舒芬太尼联合罗哌卡因对剖宫产妇血流动力学及麻醉质量的影响[J]. 全科医学临床与教育, 2018, 10(1):33-37. MIESZKOWSKI M M, MAYZNER-ZAWADZKA E, TUYAKOV B, et al. Evaluation of the effectiveness of the Quadratus Lumborum Block type I using ropivacaine in postoperative analgesia after a cesarean section-a controlled clinical study[J]. Ginekol Pol, 2018, 89(2):89-96.
张文丽, 梁子兴. 罗哌卡因联合舒芬太尼分娩镇痛对产妇产程及剖宫产率的影响[J]. 深圳中西医结合杂志, 2018, 28(15):118-120. HE Z Y, JIAO Q L, MIAO Y, et al. Clinical observation of ropivacaine compuled with sufentanil for painless childbirth[J]. Pak J Pharm Sci, 2016, 29(Suppl 2):707-709.
王粉叶. PCA泵入小剂量舒芬太尼联合罗哌卡因在分娩镇痛中的应用[J]. 临床医药文献电子杂志, 2016, 3(43):59-59. 李明亮, 尹坚银, 邹定全. 罗哌卡因联合舒芬太尼在无痛分娩中的应用效果[J]. 中国医药导报, 2019, 16(1):108-111. WILWERTH M, MAJCHER J L, VAN DER LINDEN P. Spinal fentanyl versus sufentanil for postoperative analgesia after C-section[J]. Obstet Anesth Dig, 2016, 36(4):221-228.
DOURADO A D, FILHO R L, FERNANDES R A, et al. Sufentanil in combination with low-dose hyperbaric bupivacaine in spinal anesthesia for cesarean section:a randomized clinical trial[J]. Braz J Anesthesiol, 2016, 66(6):622-627.
夏继林, 周伟, 黄国平. 罗哌卡因联合舒芬太尼硬膜外镇痛对妊高征高危产妇剖宫产术后应激反应的影响[J]. 实用临床医药杂志, 2018, 22(15):82-85. 李慧文. 罗哌卡因和舒芬太尼腰硬联合麻醉对剖宫产产妇及新生儿的影响观察[J]. 临床医药文献电子杂志, 2019, 6(40):184-186. 唐文志, 陈俊涛, 白勇. 舒芬太尼在术后ICU患者镇静镇痛中的应用[J]. 中国医药指南, 2016, 14(1):132-132. 梁皓, 亢红妮. 罗哌卡因与舒芬太尼腰-硬联合麻醉在剖宫产术中的效果[J]. 临床医学研究与实践, 2017, 2(18):49-50. 林雅丽, 丁艺, 覃淼. 舒芬太尼联合罗哌卡因术后镇痛对剖宫产产妇泌乳素的临床效果观察[J]. 河北医学, 2017, 23(6):948-951. 袁锦强, 詹敬萍, 陈飞. 罗哌卡因联合舒芬太尼在剖宫产术后镇痛中的临床效果分析[J]. 中外医疗, 2016, 35(15):4-6.
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