Efficacy of ergometrine maleate in adjuvant treatment of postpartum hemorrhage in cesarean section
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摘要: 目的 探讨马来酸麦角新碱辅助治疗剖宫产产后出血的疗效。 方法 选取80例剖宫产产后出血患者作为研究对象,按随机数字表法分为2组,各40例。对照组采用缩宫素治疗,研究组在对照组基础上联用马来酸麦角新碱治疗。比较2组产后出血量,以及生命体征、红细胞(RBC)、红细胞压积(HCT)、血红蛋白(Hb)水平和不良反应发生情况。 结果 研究组产后1、2、4、24 h的出血量均低于对照组,差异有统计学意义(P<0.05); 治疗2 h后,研究组的心率低于对照组,舒张压、收缩压高于对照组,差异有统计学意义(P<0.05); 治疗24 h后,研究组的Hb、RBC、HCT水平高于对照组,差异有统计学意义(P<0.05); 2组不良反应发生率比较,差异无统计学意义(P>0.05)。 结论 马来酸麦角新碱辅助缩宫素治疗剖宫产产后出血的效果较好,可有效减少产后出血量、稳定患者生命体征、改善血常规指标、降低不良反应发生率。Abstract: Objective To observe the efficacy of ergometrine maleate in adjuvant treatment of postpartum hemorrhage in cesarean section. Methods A total of 80 cesarean section patients with postpartum hemorrhage treated in the hospital were divided into two groups according to random number table method, with 40 cases in each group. Control group was treated with oxytocin, and research group was given ergometrine maleate based on control group. The postpartum bleeding volume, vital signs, red blood cell(RBC), hematocrit(HCT), hemoglobin(Hb)and occurrence of adverse reactions were compared between two groups. Results The postpartum bleeding volume at 1, 2, 4 and 24 h in research group was significantly lower than those in control group(P<0.05); after 2 h treatment, the heart rate of research group was lower, and the diastolic pressure and systolic pressure in research group were significantly higher than those in control group(P<0.05). After treatment for 24 h, the levels of Hb, RBC and HCT in research group were significantly higher than those in control group(P<0.05). There was no statistical difference in the incidence of adverse reactions between research group and control group(P>0.05). Conclusion Ergometrine maleate in adjuvant treatment of postpartum hemorrhage in cesarean section has better effects, it can reduce postpartum bleeding volume, stabilize vital signs, improve blood routine indexes and decrease the incidence of adverse reactions.
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Keywords:
- cesarean section /
- postpartum hemorrhage /
- ergometrine maleate /
- oxytocin /
- adverse reactions /
- vital signs
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