Efficiency observation of gauze soaked by coptis chinensis and radix lithospermi oil in treating early ulcer of patients with diabetic foot
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摘要: 目的 探讨黄连紫草油纱条治疗糖尿病足早期溃疡的临床效果。 方法 选取2017年6月—2018年6月本院收治的糖尿病足患者64例, 随机分为治疗组32例(黄连紫草油纱条)与对照组32例(碘伏消毒配合康复新液)。比较2组治疗效果及血清血管内皮生长因子(VEGF)、碱性成纤维生长因子(bFGF)的含量。 结果 治疗组、对照组总有效率分别为96.87%、84.37%, 差异有统计学意义(P<0.05)。干预后, 2组VEGF、bFGF含量均有升高,且治疗组VEGF、bFGF含量显著高于对照组(P<0.05)。 结论 黄连紫草油纱条治疗糖尿病足早期溃疡效果显著。Abstract: Objective To explore the efficiency of gauze soaked by coptis chinensis and radix lithospermi oil in treating early ulcer of patients with diabetic foot. Methods Totally 64 patients with diabetic foot from June 2017 to June 2018 in authors' hospital were selected and randomly divided into treatment group(treated with gauze soaked by coptis chinensis and radix lithospermi oil)and control group(treated with iodophor disinfection and Kangfuxin solution). The therapeutic effect and the contents of vascular endothelial growth factor(VEGF)and basic fibroblast growth factor(bFGF)were compared between the two groups. Results The total effective rates of the treatment group and the control group were 96.87% and 84.37% respectively, and there was a significant difference between two groups(P<0.05). After intervention, the contents of VEGF and bFGF increased in both groups, and contents of VEGF and bFGF in the treatment group were significantly higher than those in the control group(P<0.05). Conclusion Gauze soaked by coptis chinensis and radix lithospermi oil is effective in treating early ulcer of patients with diabetic foot.
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杨立娜, 张翠兰, 候书鹏, 等. 426例糖尿病足住院患者临床特征分析[J]. 河北医科大学学报, 2019, 40(3): 347-350. 孙晓, 张瑾. 糖尿病足患者健康教育研究进展[J]. 护理学杂志, 2019, 34(5): 108-112. 赵营宇, 辛霞, 董英, 等. 异种脱细胞真皮治疗2型糖尿病足溃疡效果观察[J]. 护理学杂志, 2019, 34(3): 7-10. Chin L C H, Boulton A J M. The diabetic foot: epidemiology, risk factors, and standards of care[M] //General Surgery. London: Springer London, 2009: 1867-1876.
杨丹, 刘竹韵, 高玲玲. 基于Web of Science数据库有关糖尿病足研究的文献计量学分析[J]. 护理研究, 2019, 33(4): 643-648. 周东华. 焦点解决护理模式对糖尿病足高危患者自我护理能力的影响[J]. 当代护士: 下旬刊, 2019(3): 32-34. Boulton A J. The diabetic foot: from art to science. The 18th Camillo Golgi lecture[J]. Diabetologia, 2004, 47(8): 1343-1353.
温聪慧, 杨营军. 湿性敷料换药法在糖尿病足换药处理中的应用效果观察[J]. 医学理论与实践, 2018, 31(24): 3675-3676. 赵炳瑞, 韩大为. 糖尿病足中医外治法治疗进展[J]. 世界最新医学信息文摘, 2018, 18(98): 139-140. 周爱民, 胡雪松, 刘本华, 等. 中医外治法在慢性心力衰竭治疗中的应用进展[J]. 实用中医药杂志, 2019, 35(3): 377-379. 张凤瑞, 杨登科, 秦建平, 等. 紫草素治疗皮肤病的研究进展[J]. 皮肤病与性病, 2019, 41(1): 29-31. 詹志来, 胡峻, 刘谈, 等. 紫草化学成分与药理活性研究进展[J]. 中国中药杂志, 2015, 40(21): 4127-4135. 常锦萍, 李建设, 田涛. 复方紫草油治疗尿布皮炎的疗效观察[J]. 世界中医药, 2018, 13(12): 3078-3080. 尹丽丽. 黄连的药理作用及现代研究进展[J]. 中医临床研究, 2016, 8(28): 144-145. 类玮玮. 紫丹纱条外敷治疗糖尿病足临床观察[J]. 中国中医药现代远程教育, 2017, 15(21): 88-90. 肖黎, 吴石白, 关小宏. 敷料在糖尿病足治疗中的应用现状及展望[J]. 医学综述, 2014, 20(20): 3762-3765. 张井香. 中药油纱条换药治疗糖尿病足溃疡及压疮36例效果观察[J]. 齐鲁护理杂志, 2016, 22(23): 123-124. 郎彦波, 李义, 宋启刚, 等. 超声清创配合中药贴敷治疗糖尿病足坏疽30例临床疗效观察[J]. 糖尿病新世界, 2015(15): 171-172. 薄颖. 中药油纱条换药治疗糖尿病足溃疡及压疮的护理分析[J]. 糖尿病新世界, 2015(1): 130-131. 席佳楠, 郝亚静, 闫雅凤. 表皮生长因子联合凡士林油纱治疗老年糖尿病患者压疮的效果观察[J]. 军医进修学院学报, 2011, 32(2): 168-169. 陈炜. 天然植物抗菌液对小鼠糖尿病足溃疡及烫伤治疗作用的研究[D]. 成都: 西南交通大学, 2016. 宋瑞捧, 沈珂珂, 马豪莉, 等. 表皮生长因子联合银离子敷料治疗糖尿病足感染的临床研究[J]. 中华医院感染学杂志, 2014, 24(16): 4033-4035.
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