不同听力曲线类型突发性聋的临床疗效分析

李凤娇; 赵永亮; 杨风波; 薛新中

doi:10.7619/jcmp.202001004

不同听力曲线类型突发性聋的临床疗效分析

1. 河南省焦作市第二人民医院耳鼻咽喉头颈外科, 河南焦作, 454000;
2. 川北医学院附属医院耳鼻咽喉头颈外科, 四川南充, 637000

基金项目:

国家自然科学基金资助项目(81470700H1304)

四川省教育厅课题(16ZB0231)

详细信息

通讯作者:
薛新中, E-mail: 306624129@qq.com

中图分类号: R764.43
计量
- 文章访问数: 311
- HTML全文浏览量: 69
- PDF下载量: 13
出版历程
- 收稿日期: 2019-11-04
- 网络出版日期: 2020-12-22
- 发布日期: 2020-08-06

Clinical efficacy analysis of different audiometric curves in sudden sensorineural hearing loss patients

1. Department of Otolaryngology and Head and Neck Surgery, Second People's Hospital of Jiaozuo, Jiaozuo, Henan, 454000;
2. Department of Otolaryngology and Head and Neck Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000

摘要

摘要: 目的分析不同听力曲线类型突发性聋患者的临床特点。方法回顾性分析186例(200耳)突发性聋患者的临床资料,根据听力曲线类型的不同将200耳分为4组,分别对其临床特征进行综合分析,并比较性别、侧别、伴发症状(耳闷、耳鸣、眩晕)、听力损失程度以及疗效分布特点。结果 186例患者(200耳)中,男115耳,女85耳; 左耳发病76耳,右耳发病96耳,双耳28耳; 伴耳鸣者191耳,伴眩晕者60耳; 低频下降组12耳,高频下降组23耳,平坦下降组63耳,全聋组102耳。200耳的治疗总有效率为36.50%, 低频下降组总有效率为41.67%, 高频下降组总有效率为30.43%, 平坦下降组总有效率为46.03%, 全聋组总有效率为31.37%。4组在性别、疗效、耳闷、耳鸣方面比较,差异无统计学意义(P>0.05), 在侧别、听力损失程度、眩晕方面比较,差异有统计学意义(P<0.01)。4组治疗后的听力水平较治疗前有不同程度改善。结论不同听力曲线类型的突发性聋发病机理不同,疗效也有不同。突发性聋患者的听力曲线以全聋型最多,低频下降型最少,其中平坦下降型疗效最好,低频下降型、全聋型次之,高频下降型最差,分型治疗有助于提供个性化的诊疗方案,为听力损失的预防及干预提供参考。
- 听力曲线类型 /
- 突发性聋 /
- 临床特征 /
- 听力损失
Abstract: Objective To analyze characteristics of different audiometric curves in sudden sensorineural hearing loss(SSNHL). Methods Retrospective analyze of 186 cases(200 ears)of SSNHL was performed, and were divided into four groups according to different audiometric curves. The clinical characteristics of these patients were analyzed, and their gender, deaf side, concomitant symptoms(ear tightness, tinnitus, vertigo), hearing loss degree and therapeutic effect distribution were compared. Results Among 186 cases(200 ears), there were 115 ears in males and 85 in females; 76 left ear, 96 right ears, and 28 bilateral ears; 191 ears complicating with tinnitus, 60 ears with vertigo; 12 ears in low-frequency descending group, 23 ears high-frequency descending group, 63 ears in flat descending group, and 102 ears in deaf group. After the treatment, the overall effective rate in 200 ears was 36.50%, with effective rate of 41.67%, 30.43%, 46.03%, and 31.37%, respectively, in low-frequency descending group, high-frequency descending group, flat descending group and deaf group. Gender, ear fullness, tinnitus, and curative effect showed no significant differences(P>0.05), but hearing loss side, hearing loss degree, as well as vertigo showed significant difference(P<0.01). Compared with pre-treatment, hearing was improved post-treatment. Conclusion Different types of hearing curve have different pathogenesis and therapeutic effect. The hearing curve of patients with sudden deafness is the most in total deafness type, and the - lowest in low-frequency decline type, of which flat decline type has the best efficacy, followed by low-frequency decline type and total deafness type, and high-frequency decline is the worst. The classification treatment is helpful to provide personalized diagnosis and treatment scheme, and provide reference for the prevention and intervention of hearing loss.
- audiogram curve type /
- sudden deafness /
- clinical characteristics /
- hearing loss

HTML全文

参考文献(26)

中华耳鼻咽喉头颈外科杂志编辑委员会, 中华医学会耳鼻咽喉头颈外科学分会. 突发性聋诊断和治疗指南[J]. 中华耳鼻咽喉头颈外科杂志, 2015, 50(6): 443-447.

李凤娇, 薛希均, 王莉, 等. 儿童突发性聋患者的预后分析[J]. 临床耳鼻咽喉头颈外科杂志, 2015, 29(22): 1931-1935.

Alexander T H, Harris J P. Incidence of sudden sensorineural hearing loss[J]. And, 2013, 34(9): 1586-1589.

Nakashima T, Sato H, Gyo K, et al. Idiopathic sudden sensorineural hearing loss in Japan[J]. Acta Otolaryngol, 2014, 134(11): 1158-1163.

陈平, 唐安洲, 郑明华, 等. 突发性聋不同听力曲线类型的临床特征及疗效分析[J]. 临床耳鼻咽喉头颈外科杂志, 2012, 26(22): 1043-1046.

周丹阳, 孙艳菊. 突发性耳聋不同分型的疗效及预后影响因素分析[J]. 中国乡村医药, 2013, 20(10): 39-42.

王大勇, 侯志强, 刘岩, 等. 青少年突发性耳聋的临床特征及疗效分析[J]. 中华医学杂志, 2013, 93(20): 1574-1576.

Bramhall N F, Kallman J C, Verrall A M, et al. A novel WFS1 mutation in a family with dominant low frequency sensorineural hearing loss with normal VEMP and EcochG findings[J]. BMC Med Genet, 2008, 9: 48-48.

García-Berrocal J R, Ramírez-Camacho R, Lobo D, et al. Adverse effects of glucocorticoid therapy for inner ear disorders[J]. ORL J Otorhinolaryngol Relat Spec, 2008, 70(4): 271-274.

Mamak A, Yilmaz S, Cansiz H, et al. A study of prognostic factors in sudden hearing loss[J]. Ear Nose Throat J, 2005, 84(10): 641-644.

Battaglia A, Burchette R, Cueva R. Combination therapy(intratympanic dexamethasone + high-dose prednisone taper)for the treatment of idiopathic sudden sensorineural hearing loss[J]. And, 2008, 29(4): 453-460.

钱怡, 钟时勋, 胡国华, 等. 突发性耳聋的分型治疗及预后分析[J]. 重庆医科大学学报, 2015, 40(8): 1159-1163.

Chung J H, Cho S H, Jeong J H, et al. Multivariate analysis of prognostic factors for idiopathic sudden sensorineural hearing loss in children[J]. Laryngoscope, 2015, 125(9): 2209-2215.

Ao M, Deng J, Qi X, et al. Clinical comparison of idiopathic sudden deafness in children and the elderly[J]. J Clin Otorhinolaryngol Head Neck Surg, 2015, 29(14): 1279-1283.

王秋菊, 兰兰, 韩冰, 等. 双侧突发性耳聋患者临床特征与预后分析[J]. 中华耳科学杂志, 2010, 8(2): 119-128.

刘海红, 张华, 莫玲燕, 等. 基于听力相关疾病就诊患者的听力曲线类型分布特征分析[J]. 临床耳鼻咽喉头颈外科杂志, 2011, 25(22): 1015-1018.

Li F J, Wang D Y, Wang H Y, et al. Clinical study on 136 children with sudden sensorineural hearing loss[J]. Chin Med J, 2016, 129(8): 946-952.

Schreiber B E, Agrup C, Haskard D O, et al. Sudden sensorineural hearing loss[J]. Lancet, 2010, 375(9721): 1203-1211.

Cho C S, Choi Y J. Prognostic factors in sudden sensorineural hearing loss: a retrospective study using interaction effects[J]. Braz J Otorhinolaryngol, 2013, 79(4): 466-470.

李莉, 张婧. 不同类型及年龄突发性耳聋患者疗效分析[J]. 中国耳鼻咽喉颅底外科杂志, 2014, 20(1): 69-71.

李庆红, 毕静, 马桂琴, 等. 低频下降突发性耳聋预后影响因素分析[J]. 临床和实验医学杂志, 2015, 14(5): 415-417.

Nagaoka J, Anjos M F, Takata T T, et al. Idiopathic sudden sensorineural hearing loss: evolution in the presence of hypertension, diabetes mellitus and dyslipidemias[J]. Braz J Otorhinolaryngol, 2010, 76(3): 363-369.

Yen Y C, Lin Y S, Weng S F, et al. Risk of sudden sensorineural hearing loss in patients with psoriasis: a retrospective cohort study[J]. Am J Clin Dermatol, 2015, 16(3): 213-220.

Lin C F, Lee K J, Yu S S, et al. Effect of comorbid diabetes and hypercholesterolemia on the prognosis of idiopathic sudden sensorineural hearing loss[J]. Laryngoscope, 2016, 126(1): 142-149.

Umesawa M, Kobashi G, Kitoh R, et al. Relationships among drinking and smoking habits, history of diseases, body mass index and idiopathic sudden sensorineural hearing loss in Japanese patients[J]. Acta Otolaryngol, 2017, 137(sup565): S17-S23.

Atturo F, Colangeli R, Bandiera G, et al. Can unilateral, progressive or sudden hearing loss be immune-mediated in origin[J]. Acta Otolaryngol, 2017, 137(8): 823-828.

施引文献(10)

期刊类型引用(9)

1.	林卿，余静. 中药在骨科患者疾病管理中的应用. 中医药管理杂志. 2023(04): 221-223 . 百度学术
2.	刘进，黄正霜，胡亚飞. 骨科活血化瘀类中药注射剂不合理应用状况调查研究. 中医药管理杂志. 2023(06): 135-137 . 百度学术
3.	王资涵，陈鑫，张伯滔，康然，朱垚. 基于数据挖掘分析神经根型颈椎病气滞血瘀证的用药规律. 实用临床医药杂志. 2023(17): 110-116 . 本站查看
4.	潘哲浩，侯燕明，王炜，倪忠根. 常用中药贴片治疗骨科疾病的药物经济学价值和安全性. 中医药管理杂志. 2023(17): 71-73 . 百度学术
5.	徐靓. 颈部整脊配合降压药物治疗高血压伴颈椎病临床观察. 光明中医. 2022(14): 2609-2611 . 百度学术
6.	徐婷婷. 2018—2021年门诊药房活血化瘀类中成药应用调查及管理措施分析. 内蒙古中医药. 2022(11): 147-149 . 百度学术
7.	邱少吒. 药物竹罐在气滞血瘀型颈椎病患者中的应用. 医学食疗与健康. 2021(02): 21-22 . 百度学术
8.	魏燕，刘雯雯，赵洋，王黛媛. 活血化瘀中药注射剂药品的不良反应情况分析. 中国社区医师. 2021(08): 102-103 . 百度学术
9.	徐军，黄移生. 蜡艾无烟灸联合当归四逆汤治疗风寒痹阻型颈椎病的效果观察. 实用医院临床杂志. 2021(04): 54-58 . 百度学术