脉络膜新生血管的光学相干断层扫描血管成像和荧光素血管造影的特征分析

龚玉静; 武炳慧; 索琰; 陆慧琴; 曲晓瑜

doi:10.7619/jcmp.201922005

脉络膜新生血管的光学相干断层扫描血管成像和荧光素血管造影的特征分析

陕西省西安市第一医院西安市眼科医院, 陕西西安, 710001

详细信息

通讯作者:
曲晓瑜, E-mail: 516717274@qq.com

中图分类号: R774.5
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出版历程
- 收稿日期: 2019-09-10
- 录用日期: 2019-10-24
- 网络出版日期: 2021-02-28
- 发布日期: 2019-11-27

Characteristics of choroidal neovascularization in optical coherence tomography angiography versus fluorescein angiography

Xi′an First Hospital, Xi′an Ophthalmological Hospital, Xi′an, Shaanxi, 710001

摘要

摘要:
目的探讨脉络膜新生血管(CNV)的光学相干断层扫描血管成像(OCTA)和荧光素血管造影(FFA)的特征。
方法回顾诊断为CNV的116例患者的临床资料，排除瘢痕期的病灶，共116眼，分析患者同期进行的OCTA和FFA检查的特征。
结果 CNV在OCTA中表现为肾小球形的最多(占48.3%), 其中病灶周围有黑晕的占64.3%; 其次为美杜莎形(占36.2%), 病灶周围有黑晕的占71.4%; 最少的为枯树枝状CNV(占15.5%), 其中病灶周围有黑晕的比例为22.2%。在FFA检查中，无源性渗漏和经典型渗漏占比分别为58.6%和41.4%, 无源性渗漏中合并出血、渗出及色素紊乱者分别占50.0%、38.2%和35.3%。OCTA中表现为肾小球形合并周围黑晕的病灶占经典型渗漏的37.5%, 表现为美杜莎形合并周围黑晕的病灶占经典型渗漏的25.0%, 表现为枯树枝状且周围无黑晕的病灶占经典型渗漏的16.7%。
结论与FFA相比, OCTA检查技术具有非接触性、扫描速度快、分辨率高的优点。
- 脉络膜新生血管 /
- 光相干断层扫描血流成像 /
- 荧光素血管造影
Abstract:
Objective To investigate the characteristics of choroidal neovascularization(CNV) in optical coherence tomography angiography(OCTA)versus fluorescein angiography(FFA).
Methods The data of 116 patients with CNV diagnosed in our hospital were retrospectively reviewed, and 116 eyes were included in study after exclusion of those in scar stages. The characteristics of OCTA and FFA conducted in theses eyes in the same period were analyzed.
Results OCTA results showed that the glomerulus-shaped CNV accounted for the most proportion(48.3%), followed by Medusa-shaped (36.2%) and withered tree-shaped(15.5%), and the darkness around lesions accounted for 64.3%, 71.4% and 22.2%, respectively. FFA showed that the proportions of passive leakage and typical leakage were 58.6%and 41.4%, respectively, and the proportions of passive leakage combined with hemorrhage, exudation and pigmentation disorder were 50.0%, 38.2% and 35.3%, respectively. OCTA showed that the ratios of glomerulus-shaped or Medusa-shaped lesions combined with darkness around lesions to typical leakage were 37.5%, 25.0%, respectively, and the withered tree-shaped lesions combined with darkness to typical leakage ratio was 16.7%.
Conclusion Compared with FFA, OCTA has the advantages of non-contact, fast scanning and high resolution.
- choroidal neovascularization /
- optical coherence tomography angiography /
- fluorescein angiography

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参考文献(9)

[1]	Tan A C S, Tan G S, Denniston A K, et al. An overview of the clinical applications of optical coherence tomography angiography[J]. Eye (Lond), 2018, 32(2): 262-286. doi: 10.1038/eye.2017.181
[2]	Sulzbacher F, Pollreisz A, Kaider A, et al. Identification and clinical role of choroidal neovascularization characteristics based on optical coherence tomography angiography[J]. Acta Ophthalmol, 2017, 95(4): 414-420. doi: 10.1111/aos.13364
[3]	Coscas G, Lupidi M, Coscas F, et al. Optical coherence tomography angiography during follow-up: qualitative and quantitative analysis of mixed type Ⅰ and Ⅱ choroidal neovascularization after vascular endothelial growth factor trap therapy[J]. Ophthalmic Res, 2015, 54(2): 57-63. doi: 10.1159/000433547
[4]	Dansingani K K, Tan A C S, Gilani F, et al. Subretinal hyperreflective material imaged with optical coherence tomography angiography[J]. Am J Ophthalmol, 2016, 169: 235-248. doi: 10.1016/j.ajo.2016.06.031
[5]	Bonini Filho M A, Adhi M, de Carlo T E, et al. Optical coherence tomography angiography in retinal artery occlusion[J]. Retina (Philadelphia, Pa), 2015, 35(11): 2339-2346. doi: 10.1097/IAE.0000000000000850
[6]	El Ameen A, Cohen S Y, Semoun O, et al. Type 2 neovascularization secondary to age-related macular degeneration imaged by optical coherence tomography angiography[J]. Retina (Philadelphia, Pa), 2015, 35(11): 2212-2218. doi: 10.1097/IAE.0000000000000773
[7]	Coscas G, Lupidi M, Coscas F. Image analysis of optical coherence tomography angiography[J]. Dev Ophthalmol, 2016, 56: 30-36. http://www.karger.com/Article/FullText/442774
[8]	De Oliveira T, Isaac D L C, Garcia J M B B, et al. Oct angiography compared to fluorescein angiography, indocyanine green angiography and optical coherence tomography in the detection of choroidal neovascularization in pigment epithelial detachment[J]. Acta Ophthalmol, 2019, 97(7): e1006-e1012. http://www.ncbi.nlm.nih.gov/pubmed/31012539
[9]	Soomro T, Talks J, Medscape. The use of optical coherence tomography angiography for detecting choroidal neovascularization, compared to standard multimodal imaging[J]. Eye (Lond), 2018, 32(4): 661-672. doi: 10.1038/eye.2018.2

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