Effect of interventional radiotherapy combined with arterial embolization in treatment of patients with arteriogenic gastric hemorrhage
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摘要:目的 探讨动脉源性胃出血患者实施放射介入联合动脉栓塞治疗的临床效果。方法 选取80例动脉源性胃出血患者作为研究对象，按治疗方案的不同分为2组，各40例。对照组采取传统内科治疗方案，研究组采取放射介入联合动脉栓塞治疗方案，对2组患者72 h内止血成功率、半年复发率、不良反应发生率和整体疗效进行统计学分析。结果 研究组患者72 h内止血成功率(100.00%)显著高于对照组(85.00%)(P < 0.05); 研究组患者出院后半年的动脉源性胃出血复发率(2.50%)显著低于对照组(20.00%)(P < 0.05); 研究组治疗期间的不良反应发生率(5.00%)显著低于对照组(27.50%)(P < 0.05); 研究组的整体治疗有效率(97.50%)显著高于对照组(77.50%)(P < 0.05)。结论 动脉源性胃出血患者实施放射介入联合动脉栓塞治疗的临床效果理想，可在72 h内成功止血，安全可靠，且复发率较低。Abstract:Objective To investigate the clinical effect of interventional radiotherapy combined with arterial embolization in treatment of patients with arteriogenic gastric hemorrhage.Methods A total of 80 patients with arteriogenic gastric hemorrhage divided into two groups according to different treatments. The control group (n=40) was treated with traditional treatment of internal medicine, and the study group (n=40) was treated with interventional radiotherapy combined with arterial embolization. The success rate of hemostasis within 72 hours, the recurrence rate in half a year, the incidence of adverse reactions and the overall efficacy of the two groups were statistically analyzed.Results The success rate of hemostasis within 72 hours in the study group was higher than that in the control group (100.00% vs. 85.00%, P < 0.05); the recurrence rate of arteriogenic gastric hemorrhage in the study group was lower than that in the control group (2.50% vs. 20.00%, P < 0.05); the incidence of adverse reactions in the study group was lower than that in the control group (5.00% vs. 27.50%, P < 0.05). The overall effective rate of treatment in the study group was higher than that in the control group (97.50%vs. 77.50%, P < 0.05).Conclusion The clinical effect of interventional radiotherapy combined with arterial embolization for patients with arteriogenic gastric hemorrhage is ideal, and it is safe and reliable in stopping bleeding successfully within 72 hours, and can reduce recurrence rate.
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表 1 2组患者72 h内止血成功率和复发率比较[n(%)]
组别 n 72 h内止血成功 复发 对照组 40 34(85.00) 8(20.00) 研究组 40 40(100.00)* 1(2.50)* 与对照组比较, *P < 0.05。 
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表 2 2组患者不良反应发生情况比较[n(%)]
组别 n 发热 腹痛 合计 对照组 40 6(15.00) 5(12.50) 11(27.50) 研究组 40 1(2.50) 1(2.50) 2(5.00)* 与对照组比较, *P < 0.05。
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表 3 2组总有效率比较[n(%)]
组别 n 显效 有效 无效 总有效 对照组 40 11(27.50) 20(50.00) 9(22.50) 31(77.50) 研究组 40 26(65.00) 13(32.50) 1(2.50) 39(97.50)* 与对照组比较, *P < 0.05。
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