Perioperative comprehensive nursing for patients with middle-staged and advanced hepatocellular carcinoma treated with transcatheter arterial chemoembolization
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摘要:目的 探讨围术期综合护理对中晚期肝癌患者经导管肝动脉化疗栓塞术(TACE)治疗后恢复情况及预后的影响。方法 选择接受TACE治疗的146例肝癌患者作为研究对象，按照随机数表法分为对照组和观察组，各73例。对照组围术期采用一般常规护理，观察组在一般常规护理的基础上采用综合护理。比较2组患者的住院时间、围术期疼痛缓解有效率、生活质量及术后并发症发生率。结果 护理后，观察组住院时间显著短于对照组(P < 0.05); 观察组围术期疼痛缓解有效率、生活质量优良率显著高于对照组(P < 0.05); 观察组术后并发症发生率显著低于对照组(P < 0.05)。结论 中晚期肝癌TACE围术期采用综合护理能够有效缩短患者住院时间，降低患者围术期疼痛水平，提高生活质量，减少术后伤口感染等并发症的发生。Abstract:Objective To explore the effect of comprehensive perioperative nursing on the recovery and prognosis of patients with middle-staged and advanced hepatocellular carcinoma after transcatheter arterial chemoembolization (TACE).Methods A total of 146 patients with hepatocellular carcinoma treated with TACE in our hospital were selected as the study subjects. According to the random number table method, the patients were divided into control group and observation group, with 73 cases in each group. The control group was given general routine nursing, while the observation group was given comprehensive nursing on the basis of general routine nursing. The hospitalization time, effective rate of perioperative pain relief, quality of life and the incidence of postoperative complications were compared between the two groups.Results After nursing, the hospitalization time of the observation group was significantly shorter than that of the control group (P < 0.05); the effective rate of perioperative pain relief, and the excellent rate of quality of life in the observation group were significantly higher than that of the control group (P < 0.05); the incidence of complications in the observation group was significantly lower than that of the control group(P < 0.05).Conclusion Comprehensive nursing during the perioperative period of TACE for middle-staged and advanced hepatocellular carcinoma can effectively shorten the hospital stay, relieve perioperative pain, improve the quality of life, and reduce the incidence of complications such as wound infections.
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表 1 2组疼痛缓解情况比较[n(%)]
疗效 对照组(n=73) 观察组(n=73) 有效 16(21.92) 43(58.90) 显效 32(43.84) 24(32.88) 无效 25(34.25) 6(8.22) 疼痛缓解有效率/% 65.75 91.78* 与对照组比较, *P < 0.05。 
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表 2 2组生活质量优良情况比较[n(%)]
组别 n 优 良 一般 差 优良 对照组 73 16(21.92) 18(24.66) 25(34.25) 14(19.18) 34(46.58) 观察组 73 43(58.90) 14(19.17) 10(13.70) 6(8.22) 57(78.08)* 与对照组比较, *P < 0.05。
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表 3 2组并发症发生情况比较[n(%)]
组别 n 肝功能损伤 呕吐 发热 肿瘤血供 合计 对照组 73 4(5.48) 6(8.22) 5(6.85) 6(8.22) 21(28.77) 观察组 73 2(2.74) 4(5.48) 3(4.11) 1(13.70) 10(13.70)* 与对照组比较, *P < 0.05。
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