Clinical significance of six blood coagulation indicatorsand blood routine test in parturient women
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摘要:目的 分析临产孕妇凝血6项及血常规检测的临床意义。方法 将本院检查的94例临产孕妇作为观察组，再选择同期在本院健康体检的100例非妊娠妇女为对照组。对所有研究对象均进行凝血6项及血常规检测，观察并比较2组凝血活酶时间(APTT)、凝血酶时间(TT)、凝血酶原时间(PT)、纤维蛋白原(FIB)、抗凝血酶Ⅲ(AT-Ⅲ)、D-二聚体(D-D)凝血6项及红细胞计数(RBC)、白细胞计数(WBC)、血红蛋白(HGB)、血小板计数(PLT)、红细胞平均体积(MCV)、红细胞分布宽度(RDW-CV)血常规指标变化情况。结果 2组凝血6项指标中，除了TT指标无显著差异外(P>0.05), 其余5项均存在显著差异(P < 0.05); 在血常规指标方面, 2组PLT指标无显著差异(P>0.05), 其余指标均有显著差异(P < 0.05)。结论 凝血6项及血常规检测能够为临床诊断妊娠期贫血、妊娠期高血压、血栓性疾病等提供重要的临床依据。通过给予及时有效的干预治疗，可将威胁孕妇以及胎儿的相关风险降到最低。Abstract:Objective To analyze the clinical significance of six blood coagulation indicators and blood routine test in parturient women.Methods A total of 94 parturient women were selected as observation group, and 100 non-pregnant women underwent physical examination in our hospital during the same period were selected as control group. Six indicators of coagulation and blood routine were performed for all participants. The changes of six indicators of coagulation such as activated partial thromboplastin time(APTT), thrombin time(TT), prothrombin time(PT), fibrinogen(FIB), antithrombase-Ⅲ(AT-Ⅲ), D-dimmer(D-D) and blood routine indexes such as white blood cell(WBC), red blood cell(RBC), hemoglobin(HGB), mean corpuscular volume(MVC), red blood cell distribution width (RDW-CV), platelets(PLT) were observed and compared between the two groups.Results There were significant differences in the other five indexes such as APTT, PT, FIB, AT-Ⅲ and D-D between the two groups(P < 0.05), except for TT (P>0.05). There was no significant difference in PLT between the two groups (P>0.05), but significant differences in other indexes were observed (P < 0.05).Conclusion Detection of six blood coagulation indicators and blood routine test can provide important clinical basis for clinical diagnosis of gestational anemia, gestational hypertension, thrombotic diseases. Timely and effective intervention and treatment can minimize the risk threatening pregnant women and fetuses.
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表 1 2组凝血6项指标比较(x±s)
组别 APTT/s TT/s PT/s FIB/(mg/dL) AT-Ⅲ/% D-D/(mg/L) 观察组(n=94) 22.13±2.26* 12.15±7.35 11.54±0.48* 418.00±36.00* 61.00±12.00* 3.35±3.16* 对照组(n=100) 34.88±1.63 12.41±0.93 12.69±0.73 282.00±53.00 82.00±11.00 0.55±0.15 APTT: 凝血活酶时间; TT: 凝血酶时间; PT: 凝血酶原时间; FIB: 纤维蛋白原; AT-Ⅲ: 抗凝血酶Ⅲ; D-D: D-二聚体。与对照组比较, *P < 0.05。 
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表 2 2组血常规指标比较(x±s)
组别 WBC/(×109/L) RBC/(×1012/L) HGB/(g/L) MCV/fl RDW-CV/% PLT/(×109/L) 观察组(n=94) 11.90±4.60* 4.01±0.88* 115.00±16.00* 81.80±6.30* 15.10±2.40* 219.00±34.00 对照组(n=100) 5.90±1.50 4.62±0.59 127.00±9.00 88.20±4.50 12.40±1.30 221.00±33.00 WBC: 白细胞计数; RBC: 红细胞计数; HGB: 血红蛋白; PLT: 血小板计数; MCV: 红细胞平均体积; RDW-CV: 红细胞分布宽度。与对照组比较, *P < 0.05。
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[1] 王辉. 临产孕妇凝血四项及血常规检测的临床意义[J]. 中国医药指南, 2018, 16(34): 118-119. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK201834093.htm [2] 张松岩. 临产孕妇凝血四项及血常规检测的临床价值分析[J]. 中国卫生标准管理, 2017, 8(11): 117-119. doi: 10.3969/j.issn.1674-9316.2017.11.070 [3] 戴隽. 临产孕妇凝血三项和血栓弹力图检测的临床意义[J]. 国际检验医学杂志, 2017, 38(7): 965-967. doi: 10.3969/j.issn.1673-4130.2017.07.038 [4] 黄宏伟. 临产孕妇凝血指标检测的临床意义[J]. 中国民康医学, 2016, 28(22): 48-49. doi: 10.3969/j.issn.1672-0369.2016.22.022 [5] 商树坤. 临产孕妇凝血四项指标的临床检测分析及意义[J]. 中国继续医学教育, 2016, 8(10): 23-24. doi: 10.3969/j.issn.1674-9308.2016.10.016 [6] 平竹仙, 王凡. 临产孕妇凝血指标检测的临床意义[J]. 国际检验医学杂志, 2015, 36(17): 2541-2542. doi: 10.3969/j.issn.1673-4130.2015.17.036 [7] 霍小琴. 临产孕妇凝血四项及血常规检测的临床价值分析[J]. 基层医学论坛, 2016, 20(3): 349-350. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLT201603049.htm [8] 陈友, 江芳华, 林琼花. 临产孕妇凝血功能检测的临床意义[J]. 医学理论与实践, 2015, 28(23): 3266-3267. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLL201523064.htm [9] 孙冬姿. 临产孕妇凝血指标检测的临床意义[J]. 医药论坛杂志, 2016, 37(1): 38-39. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYX201601017.htm [10] 胡志愿, 郭璐娣, 刘俊峰, 等. 临产孕妇凝血四项及血常规检测的临床意义[J]. 现代医院, 2013, 13(1): 46-48. doi: 10.3969/j.issn.1671-332X.2013.01.019 [11] 蔡琴. 临产孕妇凝血四项检测的临床意义[J]. 实验与检验医学, 2014, 32(4): 463-464. https://www.cnki.com.cn/Article/CJFDTOTAL-JXJL201404041.htm [12] 奚伟红. 临产孕妇凝血四项和血常规检测的临床价值分析[J]. 中国优生优育, 2014, 20(4): 226-228. doi: 10.3969/j.issn.1007-3434.2014.04.007 [13] 王晓琴. 临产孕妇凝血四项检测的临床意义[J]. 基层医学论坛, 2014, 18(5): 601-602. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLT201405043.htm [14] 梁惠霞. 临产孕妇凝血四项指标检测的临床意义[J]. 中国农村卫生, 2013(7): 53-54. https://www.cnki.com.cn/Article/CJFDTOTAL-NCWS201307029.htm [15] 张美雪. 临产孕妇血常规、CRP及凝血检测结果的临床意义[J]. 中国医药指南, 2014, 12(29): 126-126, 128. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK201429088.htm [16] 林允鹏. 临产孕妇血常规、CRP及凝血检测结果的临床意义分析[J]. 健康之路, 2016(6): 250-251. https://www.cnki.com.cn/Article/CJFDTOTAL-JKZL201606314.htm [17] 奚伟红. 临产孕妇凝血四项和血常规检测的临床价值分析[J]. 中国优生优育, 2014, 20(4): 226-228. doi: 10.3969/j.issn.1007-3434.2014.04.007 [18] 张美雪. 临产孕妇血常规、CRP及凝血检测结果的临床意义[J]. 中国医药指南, 2014(29): 126-126. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK201429088.htm [19] 魏成军. 孕妇临产前全血细胞参数及凝血4项检测的临床意义[J]. 中国民康医学, 2015, 27(12): 15-16, 40. doi: 10.3969/j.issn.1672-0369.2015.12.006 [20] 李灵香. 凝血四项和血常规在临产孕妇中的变化及临床意义探讨[J]. 中国继续医学教育, 2017, 9(12): 69-71. doi: 10.3969/j.issn.1674-9308.2017.12.035
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