Clinical observation and nursing of Chinese medicine combined with recombinant interleukin-11 in treating refractory idiopathic thrombocytopenic purpura
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摘要: 目的：探讨中药联合重组白介素－11治疗难治性特发性血小板减少性紫癜的临床疗效和护理措施。方法将52例肾性贫血难治性特发性血小板减少性紫癜患者随机分成2组，治疗组26例给予重组人白介素－11（巨和粒）治疗，皮下注射，每天1次，连用14 d，每个月为1个疗程，并口服中药汤剂（由黄芪、生地、仙鹤草、水牛角、丹皮、紫珠草等组成），日1剂，早晚分服；对照组26例只给予重组人白介素－11（巨和粒）治疗。2组均配合专科护理干预措施，均治疗2个月。结果治疗组总有效率为88．5％，对照组为65．4％，2组比较差异有统计学意义（P ＜0．05）。结论中药联合重组白介素－Ⅱ对难治性特发性血小板减少性紫癜有显著疗效。
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关键词:
- 特发性血小板减少性紫癜 /
- 难治性 /
- 重组白介素-11 /
- 中药 /
- 护理
Abstract: ABSTRACT:Objective To explore the clinical curative effect and nursing of Chinese medicine combined with recombinant interleukin-2 in treating refractory idiopathic thrombocytopenic purpu-ra.Methods 52 renal anemia refractory idiopathic thrombocytopenic purpura patients were ran-domly divided into treatment group and control group.The treatment group with 26 cases was given subcutaneous injection of recombinant human interleukin-2(Juhe Granule)for 1 time daily,con-tinuous treatment lasted for 14 days per month and 1 months was a course of treatment.Besides, Chinese medicine decoction(composed of radix astragali,radix rehmanniae,herba agrimoniae,buf-falo horn,cortex moutan,callicarpa macrophylla vahl,etc)was orally taken for 1 agent daily for 2 times in the morning and evening.The control group with 26 cases was given only recombinant hu-man interleukin-2 (Juhe Granule).The course of the treatment in the two groups was lasted for 2 months and nursing intervention measures were conducted during the treatment.Results The ef-fective rate was 88.5% in the treatment group and 65.4% in the control group.Comparison of the two groups showed that the difference was statistically significant(P <0.05).Conclusion Chinese medicine combined with recombinant interleukin-2 in treating refractory idiopathic thrombocy-topenic purpura has significant curative effect. -
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