Influence of carotid artery stenting on the life quality and cognitive function of patients with severe carotid artery stenosis
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摘要: 目的：观察颈内动脉支架成形术（CAS）对颈动脉重度狭窄患者生活质量及认知功能的影响。方法选取近两年在本院接受治疗的64例重度颈动脉狭窄患者，均行CAS治疗，术前及术后3、12个月对患者进行简易精神状态量表（MMSE）、日常生活能力量表（ADL）、词语流畅性测验（RVR）、数字广度（DS）、视觉保持测验（VRT）和生活质量量表（WHOQOL）评分。结果手术成功率高达100％，且术后无栓塞、颈内动脉血栓等并发症发生。患者术后颈动脉狭窄率降低，且颈动脉血流显著改善。治疗后3、12个月，患者的MMSE、VR及DS评分均明显升高，而ADL评分显著降低，其中治疗后12个月的升高及降低程度明显大于治疗后3个月。治疗后3个月，患者VRT正确评分及WHOQOL评分显著增加，而VRT错误评分明显降低。结论 CAS能明显改善颈动脉重度狭窄患者的认知功能及生活质量，值得临床推广应用。Abstract: Obj ective To observe the influence of carotid artery stenting (CAS)on the life quality and cognitive function of patients with severe carotid artery stenosis.Methods 64 carotid artery stenosis patients treated with CAS were collected. Mini -mental state examination (MMSE),activity of daily living scale (ADL),rapid verbal retrieve (RVR),digit span (DS),vi-sual retention test (VRT)and WHOQOL were applied for patients to assess efficacy at the time points of before operation and 3 ,12 months after operation.Results The success rate of CAS was 100%,and no complications such as embolism and internal carotid artery thrombosis were ob-served .The rate of carotid artery stenosis decreased after operation,while the carotid blood flow improved significantly.3 and 12 months after treatment,MMSE,VR and DS scores increased sig-nificantly,and ADL score decreased significantly,and the increased and decreased ranges at the time of 12 months after treatment were significantly larger than those at the time of 3 months after treatment.3 months after treatment,VRT right score and WHOQOL score increased,while VRT wrong score reduced significantly.Conclusion CAS can significantly improve the life quality and cognitive function of patients with carotid artery stenosis,so it is worthy of clinical application and popularization.
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