非小细胞肺癌脑转移165例治疗及预后分析

黄丹丹, 罗裕坤, 杨家林, 王冀川, 颜高姝, 阴骏, 陈文力

黄丹丹, 罗裕坤, 杨家林, 王冀川, 颜高姝, 阴骏, 陈文力. 非小细胞肺癌脑转移165例治疗及预后分析[J]. 实用临床医药杂志, 2014, (1): 105-108. DOI: 10.7619/jcmp.201401034
引用本文: 黄丹丹, 罗裕坤, 杨家林, 王冀川, 颜高姝, 阴骏, 陈文力. 非小细胞肺癌脑转移165例治疗及预后分析[J]. 实用临床医药杂志, 2014, (1): 105-108. DOI: 10.7619/jcmp.201401034
HUANG Dandan, LUO Yukun, YANG Jialin, WANG Jichuan, YAN Gaoshu, YIN Jun, CHEN Wenli. Treatment and prognosis analysis of 165 non-small cell lung cancer patients with cerebral metastasis[J]. Journal of Clinical Medicine in Practice, 2014, (1): 105-108. DOI: 10.7619/jcmp.201401034
Citation: HUANG Dandan, LUO Yukun, YANG Jialin, WANG Jichuan, YAN Gaoshu, YIN Jun, CHEN Wenli. Treatment and prognosis analysis of 165 non-small cell lung cancer patients with cerebral metastasis[J]. Journal of Clinical Medicine in Practice, 2014, (1): 105-108. DOI: 10.7619/jcmp.201401034

非小细胞肺癌脑转移165例治疗及预后分析

基金项目: 中国高校医学期刊临床专项资金
详细信息
  • 中图分类号: R734.2

Treatment and prognosis analysis of 165 non-small cell lung cancer patients with cerebral metastasis

  • 摘要: 目的 分析非小细胞肺癌(NSCLC)脑转移患者不同治疗方式对预后的影响.方法 回顾性分析本院收治的165例NSCLC脑转移患者的临床资料,其中90例行单纯放疗,20例行单纯化疗,55例行放化联合治疗.所有患者中,79例接受全脑放疗及脑转移灶立体定向放射治疗(WBRT+ SRT),92例接受肺部原发灶放疗.对不同治疗方式患者的生存情况进行比较,并分析预后影响因素.结果 单纯放、化疗患者中位生存期均为5个月,而同步或序贯放化疗患者中位生存期为11个月;单纯WBRT与WBRT+ SRT患者中位生存期分别为4个月和9个月,WBRT+ SRT明显优于单纯WBRT,差异有统计学意义;接受肺部原发灶放疗患者中位生存期(11个月)明显优于未接受肺部原发灶放疗的患者(4个月),差异有统计学意义.COX多因素分析发现,肺部放疗为患者独立预后因素.结论 NSCLC脑转移患者预后较差,肺部原发灶放疗是其独立预后因素.
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出版历程
  • 发布日期:  2014-07-09

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