Effect of edaravone combined with ozagrel sodium on recovery of nervous system function in patients with acute cerebral infarction
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摘要: 目的 观察依达拉奉与奥扎格雷钠联合治疗进展性脑梗死的临床疗效.方法 选择急性脑梗死患者60例,随机分为治疗组和对照组,每组30例.2组均采用常规临床治疗,在此基础上对照组给予奥扎格雷钠80 mg,加入生理盐水(NS)250 mL,静脉滴注,1次/d;治疗组在对照组治疗基础上给予依达拉奉10 mg,加入生理盐水100 mL静脉滴注,2次/d.疗程均为14 d.对2组患者治疗前后的神经功能缺损程度进行评分,并评价临床疗效.结果 2组患者治疗前美国国立卫生院卒中量表(NIHSS)评分、神经功能缺损评分(NDS)、日常生活活动能力(ADI)评分比较,差异无统计学意义(P＞0.05).2组患者治疗后NIHSS、NDS及ADL评分均优于治疗前,差异有统计学意义(P＜0.01);治疗组治疗后NIHSS、NDS及ADL评分均优于对照组治疗后,差异有统计学意义(P＜0.01).对照组治疗总有效率为53.33％;治疗组治疗总有效率90.00％.治疗组治疗总有效率明显高于对照组,差异有统计学意义(P＜0.05).结论 依达拉奉联合奥扎格雷钠治疗急性脑梗死,可明显改善患者神经功能缺损.
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Keywords:
- edaravone /
- ozagrel sodium /
- acute cerebral infarction
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