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摘要: 2型糖尿病(T2DM)是一种常见慢性进展性疾病,通常在环境因素触发下发病,近年来,其发病率在全球范围内呈逐年增高趋势.持续性高血糖是诱发并加重胰岛B细胞功能衰竭的主要危险因素之一,而口服降糖药通常难以有效控制新诊断血糖较高的T2DM患者的血糖[1].研究[2-3]表明,迅速缓解高血糖可在一定程度上减轻胰岛素的抵抗并逆转B细胞功能,而早期应用胰岛素强化治疗可快速控制血糖在正常范围内波动,减弱高血糖对胰岛B细胞功能造成的损伤,从而有效保护残存B细胞功能.本研究通过短期应用胰岛素泵强化治疗新诊断的T2DM患者,取得了满意疗效,现报告如下.
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