急性冠脉综合征患者血清胱抑素C,同型半胱氨酸和急性时相C反应蛋白水平及其影响因素研究

吕国龄; 霍正禄

doi:10.7619/jcmp.201311004

急性冠脉综合征患者血清胱抑素C,同型半胱氨酸和急性时相C反应蛋白水平及其影响因素研究

上海长海医院急诊科,上海,200433

基金项目: 中国高校医学期刊临床专项资金

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中图分类号: R541
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- 发布日期: 2013-10-14

Study on the levels and influencing factors of serum cystatin C, homocysteine and acute phase C reactive protein in patients with acute coronary syndrome

摘要

摘要: 目的探讨血清胱抑素C(Cystatin C)、同型半胱氨酸(Hcy)和急性时相C反应蛋白(Hs-CRP)在急性冠脉综合征患者血清中的水平及其影响因素.方法急性心肌梗死患者30例为急性心梗组,不稳定心绞痛患者35例为不稳定心绞痛组,排除冠心病诊断的患者20例为对照组.检测3组患者血清中Cystatin C、Hs-CRP、Hcy水平.同时检测3组患者血低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、甘油三酯(TG)、总胆固醇(Tc)的水平,并记录患者高血压病史、糖尿病史、目前吸烟史等情况.结果急性心梗组和不稳定心绞痛组的Hs-CRP、Hcy水平明显高于对照组,LDL、HDL水平明显低于对照组；急性心梗组CystatinC、TC水平明显低于对照组；不稳定心绞痛组CystatinC水平明显高于对照组；各组TG水平无显著差异.糖尿病、吸烟史、高血压史对Hcy水平变化均有影响,对Hs-CRP、Cystatin C水平变化无影响.结论急性冠脉综合征患者血清Hcy、HsCRP、Cystatin C浓度变化在一定程度上反映了动脉粥样斑块的稳定性.
- 急性冠脉综合征 /
- 粥样斑块 /
- 血清胱抑素C /
- 同型半胱氨酸 /
- 急性时相C反应蛋白
- acute coronary syndrome /
- atheromatous plaque /
- serum cystatin C /
- homocysteine /
- acute phase C reactive protein

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参考文献(12)

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文章访问数: 130
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急性冠脉综合征患者血清胱抑素C,同型半胱氨酸和急性时相C反应蛋白水平及其影响因素研究

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出版历程

Study on the levels and influencing factors of serum cystatin C, homocysteine and acute phase C reactive protein in patients with acute coronary syndrome

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出版历程

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