-
摘要: 肝硬化是由肝纤维化发展而成,是所有慢性肝脏损伤的最终病理阶段.近年发现脂联素与慢性肝病的关系非常密切,在非酒精性脂肪性肝病、慢性丙型肝炎以及乙型肝炎肝硬化中均发现脂联素浓度表达异常[1-3].本研究采用复方鳖甲软肝片对乙型肝炎肝硬化患者进行抗纤维化治疗,观察其血清脂联素浓度变化,现报告如下.
-
-
Pagano C, Soardo G, Esposito W. Plasma adiponectin is decreased in nonalcoholic fatty liver disease [J]. European Journal of Endocrinology, 2005, (1):113. Liu C J, Chen P J, Jeng Y M. Serum adiponectin correlates with viral characteristics but not histologic features in patients with chronic hepatitis C [J]. Journal of Hepatology, 2005.235. 张贵利, 李强, 李友生. 乙型肝炎肝硬化患者血清脂联素浓度与相关因素的关系 [J]. 首都医科大学学报, 2010, (6):792.doi: 10.3969/j.issn.1006-7795.2010.06.021. 中华医学会传染病与寄生虫病学分会、肝病学分会联合修订. 病毒性肝炎防治方 [J]. 中华肝脏病杂志, 2000.324. Handy J A, Saxena N K, Fu P. Adiponectin activation of AMPK disrupts leptin-mediated hepatic fibrosis via suppressors of cytokine signaling (SOCS-3) [J]. Journal of Cellular Biochemistry, 2010(5):1195. WederneyerI, Bechmann L P, Odenthal M. Adiponectin inhibits steatotic CD95/Fas up-regulation by hepatocytes:Therapeutic implications for hepatitis C [J]. Journal of Hepatology, 2009(1):140. Weber T E, Kerr B J, Spurlock M E. Regulation of hepatic peroxisome prolierator-activated receptor alpha expression but not adiponectin by dietary protein in finishing pigs [J]. Journal of Animal Physiology and Animal Nutrition, 2008(5):569. Latif H A, Assal H S, Mahrnoud M. Role of serum adiponectin level in the development of liver cirrhosis inpatients with hepatitis C virus [J]. Clinical and Experimental Medicine, 2010.
计量
- 文章访问数: 257
- HTML全文浏览量: 14
- PDF下载量: 6