64层螺旋CT联合超敏C反应蛋白、D-二聚体、同型半胱氨酸检测急性冠脉综合征患者冠状动脉斑块稳定性的临床价值

朱莉; 徐彧

doi:10.7619/jcmp.201303009

64层螺旋CT联合超敏C反应蛋白、D-二聚体、同型半胱氨酸检测急性冠脉综合征患者冠状动脉斑块稳定性的临床价值

朱莉¹,
徐彧²

1.
上海市第十人民医院,心内科,上海,200072;
2.
上海市第十人民医院,放射科,上海,200072

基金项目: 中国高校医学期刊临床专项资金

详细信息

中图分类号: R543
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- 文章访问数: 257
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出版历程
- 发布日期: 2013-05-22

Clinical value of 64-multislice spiral computed tomography combined with high-sensitivity C-reactive protein, D-dimer and homocysteine for detecting the stability of coronary arteryplaques of patients with acute coronary syndrome

ZHU Li¹,
XU Yu²

摘要

摘要: 目的探讨64层螺旋CT(64-MSCT)联合超敏C反应蛋白(hsCRP)、D-二聚体、同型半胱氨酸(Hcy)检测急性冠脉综合征(ACS)患者冠状动脉斑块稳定性的临床价值.方法进行冠脉造影和CT成像的96例患者分为ACS组31例,稳定型心绞痛(SAP)组35例,对照组30例.根据MSCT检测的冠状动脉斑块结果将ACS组和SAP组进一步分为易损斑块组、混合斑块组、稳定斑块组,每组22例.检测血清hsCRP、Hcy水平,血浆、D-二聚体水平,64-MSCT判断冠状动脉粥样硬化斑块的性质.结果 ACS组易损斑块、混合斑块的分布显著高于SAP组,稳定斑块的分布显著低于SAP组.SAP组、ACS组hsCRP、D-二聚体、Hcy水平明显高于对照组,SAP组和ACS组间也有显著差异.各斑块组hsCRP、D-二聚体、Hcy水平均明显高于对照组.易损斑块组、混合斑块组hsCRP、D-二聚体、Hcy水平明显高于稳定斑块组.易损斑块组hsCRP、D-二聚体水平明显高于混合斑块组.结论 64层螺旋CT联合超敏C反应蛋白、D-二聚体、同型半胱氨酸检测可作为冠状动脉斑块不稳定的预测指标.
- 64层螺旋CT /
- 超敏C反应蛋白 /
- D-二聚体 /
- 同型半胱氨酸 /
- 急性冠脉综合征

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参考文献(12)

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64层螺旋CT联合超敏C反应蛋白、D-二聚体、同型半胱氨酸检测急性冠脉综合征患者冠状动脉斑块稳定性的临床价值

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Clinical value of 64-multislice spiral computed tomography combined with high-sensitivity C-reactive protein, D-dimer and homocysteine for detecting the stability of coronary arteryplaques of patients with acute coronary syndrome

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