Effects of low- flow sevoflurane anesthesia and total intravenous anesthesia on hepatic and renal functions
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摘要: 目的 探讨中等时长的低流量七氟醚麻醉和全静脉麻醉( TIVA)对肝肾功能的影响.方法 100例预期手术时长120～240 min择期行腰椎间盘手术的患者,随机分为七氟醚麻醉组(S组)和TIVA组(T组),各50例.测定术前和术后24h、48 h、72 h血清尿素氮(BUN)、肌酐(Scr)、丙氨酸转移酶(ALT)、天冬氨酸转移酶(AST)、乳酸脱氧酶(LDH)和24 h尿糖、尿蛋白和尿肌酐(Ucr)水平.结果 2组患者血清AST、ALT和LDH术前与术后无明显变化.S组患者术后48 h的血清BUN,24 h和48 h的尿糖均较术前有所升高,而术后24h和48 h的Scr较术前显著升高,但均与T组无显著差异.2组术后Ucr均较术前明显升高,但2组间无显著差异.结论 中等时长的低流量七氟醚麻醉与TIVA患者的肝肾功能的影响是相似的.
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