白细胞介素-6(IL-6)及(sIL-6R)与胆管癌

杜囚鹏, 贺春燕, 刘海峰, 邓京, 屈亚威, 高洪兰

杜囚鹏, 贺春燕, 刘海峰, 邓京, 屈亚威, 高洪兰. 白细胞介素-6(IL-6)及(sIL-6R)与胆管癌[J]. 实用临床医药杂志, 2012, (1): 30-32. DOI: 10.3969/j.issn.1672-2353.2012.01.008
引用本文: 杜囚鹏, 贺春燕, 刘海峰, 邓京, 屈亚威, 高洪兰. 白细胞介素-6(IL-6)及(sIL-6R)与胆管癌[J]. 实用临床医药杂志, 2012, (1): 30-32. DOI: 10.3969/j.issn.1672-2353.2012.01.008

白细胞介素-6(IL-6)及(sIL-6R)与胆管癌

详细信息
  • 中图分类号: R329.11 R735.8

  • 摘要: 随着分子生物学的发展,白细胞介素-6(IL-6)和(sIL - 6R)的分子结构及其生物学作用的研究取得了很大的进展.白细胞介素-6(IL-6)及其(sIL - 6R)属细胞因子家族,其中白细胞介素-6(IL -6)是一种多效性细胞因子,其参与几乎所有器官的生理活动,同时它们在外伤、感染、免疫反应、炎症、造血、冠心病及神经疾病,妊娠问题和肿瘤中也起到重要的作用.它们影响了许多疾病的发生、发展.因此,在一些疾病中,调节白细胞介素-6(IL -6)及其可溶性受体(sIL -6R)可能成为一个创新的治疗策略,尤其是其促肿瘤生长作用,使之成为抗肿瘤治疗中重要的细胞因子之一[1].高水平白细胞介素-6(IL -6)及其可溶性受体(sIL - 6R)在许多肿瘤患者的外周血及体液中可以检测到,并且可以提示患者预后不良.此外,IL -6水平的升高,与几种肿瘤表型特征密切相关,本文就其近几年在肿瘤方面的相关研究,特别是与胆管癌的关系进行综述[2].
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出版历程
  • 发布日期:  2012-04-26

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