The study of radial artery spasm vasodilator intervention
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摘要: 目的 以桡动脉造影法观察不同血管扩张剂对桡动脉的解痉效果,明确血管扩张剂对RAS的作用.方法 接受经桡动脉途径介入治疗的患者180例.随机分人A组(硝酸甘油200 μg),B组(尼卡地平200 μg)和C组(硝酸甘油100 μg+尼卡地平100μg)各60例.常规桡动脉造影后分别鞘入协定药物.给药后1 min、2 min分别行桡动脉造影.比较3组患者给药前、给药后1 min、2 min桡动脉正常参考段及痉挛段的直径变化.结果 对于桡动脉正常参考段,A、B组给药后1min、2min直径显著增加(P＜0.05)；C组在给药后较给药前直径显著增加(P＜0.05),但给药后1 min、给药后2min无显著差异(P＞0.05)；对于桡动脉痉挛段,各组内给药前、给药后1min、给药后2min桡动脉直径均存在显著统计学差异(P＜0.05),且给药2min后A组、C组的痉挛段直径显著大于B组(P＜0.05).结论 硝酸甘油及尼卡地平均具有明显扩张桡动脉的作用,但2者联合应用有更大优势.
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