The clinical significance of ankle-brachial index in diagnosing lower extremity artery disease in diabetic patients
-
摘要: 目的 了解踝肱指数(ABJ)在诊断2型糖尿病(T2DM)患者下肢动脉病变中的意义及影响因素.方法 选择300例T2DM患者,测定足背动脉与肱动脉的比值,有1侧ABI＜0.9即纳入低ABI组,2侧ABI均≥0.9者为对照组.比较2组体重指数(BMI)、腰臀比(WHR)、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1c),以及相关血脂水平.结果 ABI＜0.9者78例(低ABI组),ABI＞0.9者222例(对照组).2组年龄、糖尿病病程、TG、LDL-C、舒张压、2hPG差异有统计学意义；2组性别比、BMI、WHR、收缩压、TC、HDL-C无统计学差异.逐步回归分析显示:年龄、病程、LDL-C是影响ABI的独立因素.结论 ABI是诊断糖尿病患者下肢动脉病变的可靠指标.下肢动脉硬化加剧的主要因素为年高龄、病程长、脂代谢紊乱及高血糖.
-
-
张雄伟, 陈乔, 张以善. 踝臂指数检测对下肢动脉疾病的诊断价值 [J]. 实用临床医药杂志, 2009(8):33.doi: 10.3969/j.issn.1672-2353.2009.15.009. Genuth S, Alberti KG, Bennett P. Follow-up report on the diagnosis of diabetes mellitus [J]. Diabetes Care, 2003, (11):3160. Pearson TL. Ankle brachial index as a prognostic tool for women with coronary artery disease [J]. Journal of Cardiovascular Nursing, 2010(1):20. Dachun Xu, Jue Li, Liling Zou. Sensitivity and specificity of the ankle--brachial index to diagnose peripheral artery disease:a structured review [J]. Vascular Medicine, 2010(5):361. Ismail HM, Jackson K, Smith D. Diagnosis and treatment of peripheral arterial disease compared with other atherosclerotic vascular diseases in a university primary care clinic [J]. Journal of Investigative Medicine, 2006(5):255.doi: 10.2310/6650.2006.05049. Ostchega Y, Paulose-Ram R, Dillon CF. Prevalence of peripheral arterial disease and risk factors in persons aged 60 and older:data from the National Health and Nutrition Examination Survey 1999-2004 [J]. Journal of the American Geriatrics Society, 2007(4):583.doi: 10.1111/j.1532-5415.2007.01123.x. 吴茂红, 王奉云, 孙磊. 2型糖尿病患者餐后高脂血症与颈动脉粥样硬化病变及纤溶活性关系的研究 [J]. 山东大学学报(医学版), 2007(5):503.doi: 10.3969/j.issn.1671-7554.2007.05.018. 沙的汉, 张元. 2型糖尿病下肢血管病变发生率及危险因素分析 [J]. 海南医学院学报, 2008(5):539.doi: 10.3969/j.issn.1007-1237.2008.05.021. 张红, 李锦华, 陈越. 踝肱指数评价糖尿病下肢动脉病变危险因素的临床价值 [J]. 广西医学, 2009(1):45.doi: 10.3969/j.issn.0253-4304.2009.01.024. 赵琪, 胡增祥, 窦静. 2型糖尿病合并下肢动脉病变与踝肱指数的关系 [J]. 白求恩军医学院学报, 2010(5):351.doi: 10.3969/j.issn.1672-2876.2010.05.023.
计量
- 文章访问数: 167
- HTML全文浏览量: 25
- PDF下载量: 9
下载:
苏公网安备 32100302010246号
