-
摘要: 目的 评价第三代β受体阻滞剂卡维地洛治疗扩张型心肌病充血性心力衰竭的临床疗效.方法 28例扩张型心肌病充血性心力衰竭患者,随机分为常规治疗组和卡维地洛组,检测治疗前后临床心功能、左心室功能及结构和血浆脑钠素的变化.结果 治疗12月卡维地洛组各项指标治疗前后比较差异均有显著性(P<0.05); 卡维地洛组左心室功能及结构改善效果优于常规治疗组(P<0.05).结论 卡维地洛能够明显改善扩张型心肌病充血性心力衰竭患者心脏收缩和舒张功能,逆转左室重构.
-
-
胡大一, 马长生. 心脏病学实践2002--规范化治疗 [M]. 北京:人民卫生出版社, 2002.329. Kohno T, Yoshikawa T, Yoshizawa A. CarvediLoL exerts more potent antiadrenergic effect than metoproLoL in heart faiLure [J]. Cardiovascular Drugs and Therapy, 2005(5):347.doi: 10.1007/s10557-005-4761-9. Remme W J, Riegger G, HiLdebrandt P. The beninefits of earLy combination treatment of carvediLoL and ACE-inhibitor in miLd heart faiLure and Left ventricuLar systoLic dysfunction [J]. Cardiovascular Drugs and Therapy, 2004(1):57.doi: 10.1023/B:CARD.0000025756.32499.6f. SLiwa K, Norton G R, Kone N. Impact of initiation carvediLoL before angiotensin-converting enzyme inhibitou therapy on cardiac function in newLy diagnosed heart faiLure [J]. Journal of the American College of Cardiology, 2004(9):1825.doi: 10.1016/j.jacc.2004.05.087. David M Kaye, Leonie Johnston, Gautam Vaddadi. Scientific Contributions:Mechanisms of CarvediLoL Action in Human Comgestive Heart FaiLure [J]. Hypertension, 2001.1216. NG BeLLenger, K Rajappan, SL Rahman. Effects of carvediLoL on Left ventricuLar remodeLing in chronic stabLe heart faiLure:a cardiovascuLar magnetic resonance study [J]. Heart, 2004, (7):750.doi: 10.1136/hrt.2003.022269. Logert D, Saudubray C, Beyne P. Comparative vaLue of DoppLer echocardiography and B-type natriuretic peptide assay in the etioLogic diagnosis of Acute dyspneaL [J]. Journal of the American College of Cardiology, 2002, (10):1794.doi: 10.1016/S0735-1097(02)02482-8.
计量
- 文章访问数: 142
- HTML全文浏览量: 22
- PDF下载量: 6