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摘要: 本研究参照美国临床实验室标准化委员会(CLSI)推荐的肉汤稀释法M38-A[1]方案,检测AMB、NAT、ICZ及FCZ对眼科常见镰刀菌的体外抗菌活性,现报告如下.
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National Committee for Clinical Laboratory Standards. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Conidium-forming Filamentous Fungi [M]. Approved Standard M38–A.PA, USA:Wayne, 2002. Lass-Florl C, Kofler G, Kropshofer G. In-vitro testing of suscepti bility to amphotericin B is a reliable predictor of clinical outcome in invasive aspergillosis [J]. Journal of Antimicrobial Chemotherapy, 1998(4):497.doi: 10.1093/jac/42.4.497. Denning D W, Radford S A, Oakley K L. Correlation between in-vitro susceptibility testing to itraconazole and in-vivo outcome of Aspergillus fumiga tus infection [J]. Journal of Antimicrobial Chemotherapy, 1997(3):401.doi: 10.1093/jac/40.3.401. Pujol I, Guarro J, Sala J. Effects of incubation temperature, inoculum size, and time of reading on broth microdilution susceptibility test results for amphotericin B fgainst Fusarium [J]. Antimicrobial Agents and Chemotherapy, 1997(4):808. Musa MO, Al Eisa A, Halim M. The spectrum of Fusarium infection in immunocompromised patients with haematological malignancies and in non-immunocompromised patients:a single institution experience over 10 years [J]. British Journal of Haematology, 2000(3):544.doi: 10.1046/j.1365-2141.2000.01856.x. Xuguang S, Zhixin W, Zhiqun W. Ocular fungal isolates and antifungal susceptibility in northern China [J]. American Journal of Ophthalmology, 2007(1):131.doi: 10.1016/j.ajo.2006.09.042. Denning D W, Radford S A, Oakley K L, Hall L Johnson E M Warnock D W. Correlation between in-vitro susceptibility testing to itraconazole and in-vivo outcome of Aspergillus fumigatus infection [J]. Journal of Antimicrobial Chemotherapy, 1997.401.doi: 10.1093/jac/40.3.401.
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