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摘要: 热休克蛋白(HSPs)是一类在生物进化过程中极为保守的蛋白质,其广泛存在于原核和真核生物细胞中,在应激状态下可被诱导表达,因此又称应激蛋白(SP).HSPgp96是HSPs家族的重要成员.本研究采用免疫组织化学法检测胃癌中HSPgp96, 并结合患者的临床和病理资料分析与探讨HSPgp96在胃癌的发生、发展过程中的作用以及与胃癌耐药性的关系和胃癌预后的判断.将有助于探讨HSP在胃癌中的作用及对开发新的抗癌方法有着重要的意义.
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