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摘要: 不稳定型心绞痛(UAP)是介于急性心肌梗死(AMI)与稳定型心绞痛之间的一种表现.UAP急性期应用肝素和/或口服小剂量阿司匹林可显著减少AMI和顽固性心绞痛的发生[1],但需常规监测凝血酶原时间等指标,出血副作用多.
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Aspirin or both to treat acute unstable angina [J]. New England Journal of Medicine, 1998.1105.doi: 10.1056/NEJM198810273191701. Merlini PA, Bauer KA, Oltrona L. Persistent activation of coagulation mechanism in unstable angina and myocardial [J]. Circulation, 1994.61. Hirsh J, Levine MN. Low molecular heparin [J]. Blood, 1992.79, 1. Fareed J, Hoppensteadt DA. Pharmacology of low molecular weight heparins [ J ] [J]. Seminars in Thrombosis and Hemostasis, 1996, (Suppl 2):13. Quyyumi A A, Diodati J G, Lakatos E. Angiogenic effects of LMWH in patients with stable coronary disease A pilot study [J]. Journal of the American College of Cardiology, 1993.22, 635. 钟宁, 高海青. 低分子量肝素临床应用进展 [J]. 心血管病学进展, 1998(3):151.
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