SPLENIC MANTLE CELL LYMPHOMA:A CLINIC OPATHOLOGICAL STUDY
-
摘要: 目的:探讨脾脏套细胞淋巴瘤(SMCL)的临床病理特征、诊断和鉴别诊断.方法:对3例SMCL进行临床、组织病理和免疫组化分析.结果:男性1例,女性2例,平均年龄59.67岁.3例除脾脏肿大外,还伴有骨髓及外周血的侵犯.镜下特征为形态单一的瘤细胞呈弥漫性和/或结节性生长,瘤细胞免疫表型特征为CD5(+),cyclinD1(+),IgD(+).结论:诊断SMCL必需结合组织学特点和免疫表型,还需与滤泡性淋巴瘤、小淋巴细胞性淋巴瘤、脾边缘区B细胞淋巴瘤鉴别.
-
-
Jaffe E, Berard C, Harris N. Society for Hematopathology program [J]. American Journal of Surgical Pathology, 1997.114.doi: 10.1097/00000478-199701000-00014. Weisenburger DD, Nathwani BN, Diamond LW. Malignant lymphoma intermediate lymphocytic type A clinicopathologic study of 42 cases [J]. Cancer, 1981.1415.doi: 10.1002/1097-0142(19810915)48:6<1415::AID-CNCR2820480625>3.0.CO;2-N. Frizzera G. Recent progress in lymphoma classification [J]. Current Opinion in Oncology, 1997.9, 392.doi: 10.1097/00001622-199709050-00002. Bosch F, Lopez GA, Gampo E. Mantle cell lymphoma Presenting features response to therapy and prognostic Factors [J]. Cancer, 1998, (3):82, 567.doi: 10.1002/(SICI)1097-0142(19980201)82:3<567::AID-CNCR20>3.0.CO;2-Z. Vasef M, Medeiros L, Koo C. CyclinD1 immunohistochemical staining is useful in distinguishing mantle cell lymphora from other low-grade B cell neoplasms in bone marrow [J]. American Journal of Clinical Pathology, 1997.302.
计量
- 文章访问数: 146
- HTML全文浏览量: 23
- PDF下载量: 14